Ryan Mayers Email and Phone Number
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I am a molecular neuroscientist interested in how genetic variants associated with major neurodegenerative disorders disrupt intracellular trafficking and organellar dynamics to contribute to disease progression. I use robust skills in human cell culture, advanced microscopy approaches, and classical molecular biology and biochemistry approaches to address these questions.Currently, I am a PhD candidate in Brian Polster’s lab at the University of Maryland School of Medicine, where I study how disruptions in mitochondrial bioenergetics, structure, and mitochondrial-lysosomal interactions contribute to neuroinflammation in Alzheimer's Disease, Lewy Body Dementia, and traumatic brain injury. I previously completed my MS in Biotechnology in Evangelos Kiskinis's lab at Northwestern University, where I worked on nuclear import and cytoskeletal deficits in motor neuron models of ALS.
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Phd Candidate, Polster LabUniversity Of Maryland School Of MedicineBaltimore, Md, Us -
President'S Entrepreneurial FellowUniversity Of Maryland School Of Medicine Oct 2024 - PresentBaltimore, Maryland, United States -
Phd Candidate, Polster LabUniversity Of Maryland School Of Medicine Jul 2020 - PresentBaltimore, Maryland, United StatesCurrently a Neuroscience PhD student in Prof. Brian Polster's lab (Department of Anesthesiology)I use a mixture of fluorescence microscopy, iPSC-derived and immortalized microglial culture, platereader-based respirometry, and classical molecular biology and biochemical assays to assess dysfunctional mitochondrial bioenergetics and dynamics resulting from microglial pro-inflammatory activation or genetic ablation of Alzheimer's Disease and Lewy Body Dementia risk factor genes. In parallel, I also study the mechanism of action of several known or candidate mitochondrial therapeutics to explore their potential for repurposing as neuroprotective interventions in neurodegenerative disease and injury. -
Graduate Teaching AssistantUniversity Of Maryland School Of Medicine Aug 2023 - Dec 2023Baltimore, Maryland, United StatesTeaching assistant for GPLS 737, "Proseminar in Experimental Design"This is a required course for second-year neuroscience PhD students, and covers the basics of hypothesis design and grant-writing, with a core focus on NIH-style Specific Aims and Research Strategy pages. -
Graduate Research Assistant, Kiskinis LabNorthwestern University Dec 2018 - Aug 2020Chicago, IllinoisWorked in the Neurology department as a part of Prof. Evangelos Kiskinis's research group• Developed human stem cell models to test the necessity and sufficiency of genetic variants of the ALS-associated gene NIMA-related kinase 1 (NEK1) in the context of human motor neurons. • Explored the role ALS-related NEK1 genetic variants play in cellular function. Utilized confocal imaging and cell-based functional assays to examine perturbations in mechanistic pathways in mutant NEK1 motor neurons and corresponding isogenic controls.• Contributed to a publication in Science Advances: https://www.science.org/doi/10.1126/sciadv.adi5548 -
Graduate Teaching AssistantNorthwestern University Sep 2019 - Dec 2019Greater Chicago AreaTeaching assistant position for MBIOTECH 410, "Technology Commercialization Fundamentals."This is a core course for first year students in the Master of Biotechnology Program, and covers the basics of bringing a new therapy to market. -
Intramural Research Training Award Postbac FellowNational Institutes Of Health (Nih): Intramural Research Program (Irp) Jun 2017 - Sep 2018Bethesda, MarylandWorked in the National Institute on Aging's Laboratory of Neurogenetics, Cell Biology & Gene Expression Section under Dr. Mark Cookson.This group studies the genetics and gene regulation of Parkinson’s disease• Cloned, sequenced, and tested plasmids for candidate genes of interest in mammalian cell lines (iPSC, HEK293FT) via canonical molecular biology and microscopy techniques• Modified CRISPR/Cas9 plasmids to utilize a more efficient editing strategy for iPSCs -
Undergraduate Research Assistant, Betley LabUniversity Of Pennsylvania Feb 2016 - May 2017Philadelphia, PennsylvaniaWorked in the Biology department as a part of Prof. J. Nicholas Betley's research group.This lab is a neurobiology group, studying the underpinnings of survival-related behaviors in mice• Employed optogenetic and open-field assays to study gut motility and locomotor activity• Developed novel protocols to identify neuronal subpopulations of interest• Built and programmed devices to measure stereotyped mouse behaviors -
Undergraduate Research Assistant, Linksvayer LabUniversity Of Pennsylvania Sep 2014 - Dec 2015Philadelphia, PennsylvaniaWorked in the Biology department as a part of Prof. Timothy Linksvayer's research group. This lab is an evolutionary biology group, studying the origins of social behavior in Monomorium pharaonis• Developed novel behavioral assay for phenotypes of interest using 3D design and printing
Ryan Mayers Skills
Ryan Mayers Education Details
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Neuroscience -
Biotechnology -
Biology (Neurobiology)
Frequently Asked Questions about Ryan Mayers
What company does Ryan Mayers work for?
Ryan Mayers works for University Of Maryland School Of Medicine
What is Ryan Mayers's role at the current company?
Ryan Mayers's current role is PhD Candidate, Polster Lab.
What is Ryan Mayers's email address?
Ryan Mayers's email address is rs****@****ail.com
What is Ryan Mayers's direct phone number?
Ryan Mayers's direct phone number is +131285*****
What schools did Ryan Mayers attend?
Ryan Mayers attended University Of Maryland School Of Medicine, Northwestern University, University Of Pennsylvania.
What skills is Ryan Mayers known for?
Ryan Mayers has skills like Microsoft Office, Data Analysis, Microsoft Powerpoint, Public Speaking, Mammalian Cell Culture, Molecular Cloning, Confocal Microscopy.
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Ryan Mayers
Planning And Special Projects Manager, Regional Transportation Agency Of Central MarylandWashington Dc-Baltimore Area5dot.gov, yahoo.com, ncdot.org, ncdot.gov, ncdot.gov3 +191970XXXXX
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