Santanu Raychaudhuri

Santanu Raychaudhuri Email and Phone Number

Principal Investigator & Senior Scientist
Santanu Raychaudhuri's Location
United States, United States
Santanu Raychaudhuri's Contact Details
About Santanu Raychaudhuri

I have been cultivating biological sciences and their technologies through cutting edge research and development using their applications in academics and industry with an aim to improve human health.Making an immediate contribution in a challenging leadership position in Biotechnology or Pharmaceutical environments including Academics that would utilize my extensive experiences in project management, leadership, both performing and leading scientific experiments. My main goal is the drug development, particularly in Anti-Viral therapeutics, Cancer therapeutics and Metabolic Diseases. Currently I am involved in preclinical drug development in University-Industry set up and collaboration.Strength Includes: • Preclinical studies, mechanism of actions, cell-based assays and therapeutics • Background in molecular biology, biochemistry, cell biology, Virology and immunology • Details in vitro and in vivo studies: experiences in rodent animals • Detailed understanding in the drug development processes and clinical trials • Extensive experiences in scientific research processes, writings and federal regulations • Extensive hands on experiences in research and development including scientific leadership • Working experiences in cancer biology, and target pathways;• Expert in exploring cellular and molecular mechanisms in cancer and metabolic pathways • Expert in cell culture, cell-based assays, biochemical and immunological techniques • Self-motivated and demonstrated leadership in therapeutic virus-mediated cancer research• Extensive experiences in various Viral Vectors manipulations for vaccine and drug discovery research• Design, manipulations, and expressions of large biologic molecules including monoclonal antibodies • Experienced in diagnostic & bio-marker studies for infectious and metabolic diseases by Exosome-pathway • Computer handling in R & D and statistical analyses• Excellent written and oral communication skills

Santanu Raychaudhuri's Current Company Details

Principal Investigator & Senior Scientist
Santanu Raychaudhuri Work Experience Details
  • Virovek, Inc.
    Associate Director
    Virovek, Inc. Nov 2021 - Oct 2023
    United States
    Gene Therapy Vectors
  • Department Of Biotechnology, Government Of India
    Professor
    Department Of Biotechnology, Government Of India Jul 2015 - Dec 2018
    North East Universities, India
    Research & Teaching Graduate and Undergraduate University Students
  • Ucla
    Professional Scientist
    Ucla Aug 2005 - May 2014
    Ucla School Of Medicine
    Mammalian positive strand RNA virus gene regulation: Molecular targeting of the anti-virus therapeutics Development of Hepatitis C NS5A inhibitors. The molecular etiology of hepatocellular carcinoma (HCC) caused by hepatitis C. Mechanisms of actions of IRES (Internal Ribosome Entry Sites) mediated RNA translation. Development of artificial small IRES element of high biological activity: construction of HCV genome harboring artificial IRES directing high level of protein synthesis and thus directing synthesis of virus in cell culture systemCellular IRES: GLUT, VEGF and TFIID. Molecular chaperones in the cellular RNA translation in the event of stress conditions. Mechanism of actions of molecular chaperones in both viral and cellular RNA translations Epigenetic control of gene expression in higher eukaryotes. Involvement of genetic and epigenetic events in normal and pathophysiological conditions in mammals The micro-RNA mediated gene silencing: Mechanism of actions of micro-RNA in the inhibition of the specific cellular RNA translation under stress conditionsThe role of microRNA in HCV development and progression in host liver cells. Role of micro-RNA in the stem cells proliferation and differentiationHCV-mediated liver carcinogenesis. Hepatic Stem cells and how HCV affects this group of cells in normal and pathophysiological conditionsMechanism of actions of HCV-IRES inhibitors and the proposition of gene therapy in HCC patientsThe plant anti-oxidant Quercetin mediated inhibition of hepatitis C. Mechanism of actions of this group of inhibitor in the host-cell interaction. The role of Quercetin in HCV morphogenesis. The encapsidation signal for hepatitis C. The mechanism of action of HCV encapsidation.The mechanism of HCV assembly/morphogenesis of Hepatitis CViral mediated (HCV, HIV, and DNA viruses) Thymidine Kinase membrane upregulation: TK-1 mAb therapy as an anti-cancer drug
  • Ucla
    Postgraduate Researcher; Microbiology, Immunology And Molecular Genetics
    Ucla Jun 2002 - Jul 2005
    Greater Los Angeles Area
    Molecular virology in positive-strand RNA viruses and the mechanism of actions of its inhibitors. Translational control of gene expressions in mammals.Research Topics:Mammalian positive strand RNA virus gene regulation in replication, transcription and translational control with the emphasis on HCV and Polio virus. Molecular targeting of the anti-virus therapeutics in HCVDevelopment of Hepatitis C NS5A inhibitors. The molecular etiology of hepatocellular carcinoma (HCC) caused by hepatitis C. Expression and purifications of all structural and non-structural HCV proteins in E. coli and Hepatic cell-lines. Structure-function analysis of Core and NS5A in-vitro and in-vivo. Signal transduction pathways modulated by these regulatory proteins of the host systems.Mechanisms of IRES (Internal Ribosome Entry Sites) mediated RNA translation. Translational inhibitors for positive strand RNA viruses. Development of artificial small IRES element of high biological activity for functional analysis of translational regulation of protein synthesis: construction of HCV genome harboring artificial IRES and/or mutations directing high level of protein synthesis and thus high-titer virus.Cellular IRES: VEGF and TFIID. Molecular chaperones in the cellular RNA translation in the event of stress conditions. Mechanism of actions of molecular chaperones in both viral and cellular RNA translations.Publications:Raychaudhuri S, Fontanes V, Barat B, Dasgupta A (2009). Cancer Research. 69: (5). March 1, 2057-2063. Izumi RE, .... Raychaudhuri S, and Dasgupta A (2004), Journal of Virology, 78 (7): 3763-76. Raychaudhuri S, Fontanes V......Dasgupta A (2006). BBRC, 350 (3), 788-95. Kundu K, Raychaudhuri S, Tsai W, Dasgupta A (2005), Journal of Virology, 79(15):9702-13. Sharma*, R., Raychaudhuri, S*. and Dasgupta, A (2004). Virology, 320, 195-205. *equal contribution Weidman MK, Sharma R, Raychaudhuri S, ..... Dasgupta A (2003). Virus Research, 95, 75-85.
  • Memorial Sloan-Kettering Cancer Center
    Sloan-Kettering Rockefeller Institute; Sr. Research Tech
    Memorial Sloan-Kettering Cancer Center Nov 1998 - Jun 2001
    New York City
    In vitro assembly of replication complexes using baculovirus purified proteinsUnderstanding of cell-cycle regulation of DNA replication initiation and mitosis progressionCell biology of replication initiation proteins and their impact on cell cyclePublications:Fien K, Cho YS, Lee JK, Raychaudhuri S, Tappin I, Hurwitz J. (2004), Primer utilization by DNA polymerase alpha-primase is influenced by its interaction with Mcm10p. Journal of Biological Chemistry, 279(16):16144-16153.Keong-Yeop Moon, Daochun Kong, Joon-Kyu Lee, Santanu Raychaudhuriand Jerard Hurwitz (1999), Proc. Natl. Acad. Sci. (USA), 96(22), 12367-72. Identification and reconstitution of the origin recognition complex from S. pombe.Santanu Raychaudhuri (1999). Cold Spring Harbor Laboratory. The origin recognition complex of S. pombe: the importance of Orc3 and Orc6 subunits. Santanu Raychaudhuri (1999). Cold Spring Harbor Laboratory. Purification of the origin recognition complex from S. pombe.

Santanu Raychaudhuri Skills

Chromatography Qpcr Dna And Rna Molecular Virology Cap Fungal Highly Focused Undergraduate Knock Outs Slides Infectious Diseases Students Clinical Research Gst Dec Alpha Stress Natural Resources Clinical Development Yeast Microbiology Replication Acid Cat Design Pregnancy Loss Stimulation Initiation Powerpoint Antibodies Isolation Sun Microsystems Troubleshooting System Compliances Muscle Rabbit Functional Analysis Medicine Oncology Acad Drug Development Epub Transcriptional Regulation Protein Expression Carcinogenesis Pro*c Primer Design Los Angeles Mechanisms Real Time Pcr Dna Replication Blocks Yahoo C Viruses Coordination Recombinant Dna Tissue Cdna Communication Epigenetics Scientific Purification Das Molecular Biology Enzyme Kinetics Insect Cells/ Baculovirus Pages Surface Biochemistry Iso And Cdc Safety Regulations Structure Function Of Proteins Usa Regulations High Throughput Screening International Google Groups Data Management Start Ups Micro Rna Analysis By Ht Methods Guidelines Technical Writing Two Hybrid/one Hybrid Systems San Francisco Microsoft Word Cell Based Gene Silencing Pharmaceutics Bioinformatics In Vitro Connecticut Fluorescence Microscopy Fda Chip Tissue Culture Stem Cells Mechanism Of Actions Of Drugs Writing Conciseness Screening Chromatography Techniques Printing Chemistry Strain Sirna Non Clinical Thesis Symposium Strand Rna Immunohistochemistry Sequencing Cancer Cellular Communications Pacs Glp Mouse Protein Chemistry Sorting Shrna Cell Cycle Blood Results Oriented Gene Therapy Entry Pcr Mirna Validation Gene Delivery Gcp Bsl3 Laboratory And Performing Lab Audits Editing Gcps Conferences Cloning Research System Monitoring Anova Binding Written Molecular Metabolism Western Blotting Fix Protocol Phosphorylation Immunofluorescence Baculovirus Dna Sheet Posters Working Knowledge Of Gmp/glp Time Management Orc Molecular Cloning Bose Mechanism Glucose Presentations Ddr Therapists Targeted Advertising Nuclear Efficient Biology Heat Multi Tasking T Test Dismissal Treating San Diego Delineation Structural Engineering Hcv Libraries Antigen Anti Viral Therapeutics Culture Immunotherapy Biomarkers Yeast Strain Generations Nucleus Quality Results Signalling Propagation Ps3 Facs Analysis Hepatology Ctms Biotechnology Translation Hepatitis C Metabolic Syndrome Sep Ira Mammalian Cross Functional Team Leadership Microbiologists Organizational Structure Detection Texas Shock Immunoprecipitation In Vivo Model Of Cancer Science Physiology Localization Nls Skype Hiv Sop Gel Publications Xenografts Factor Instrumentation Receptor Binding Assays Healthcare Utilization Element Fluorescence Chromatin Immunoprecipitation Techniques Microsoft Excel Progression Transcription Technical Reports Viral Vectors Cell Based Assays Msc Medicinal Chemistry Assembly Virus Protein Purification American Transitioning Analysis Chromatin Immunoprecipitation Deregulation Laboratory R Affinity Foot Implications Analytical Techniques Data Analysis Managerial Finance Cell Culture Origin Classical Characterization Regulatory Requirements Mutagenesis Drug Discovery Expressions Genetics Flow Cytometry Liver Gfp Bsl2 Internal Audit Cancer Research Pathway Protocol Writing Code Logic Synthesis E. Coli Irb New York Reviews Cervical Cancer Academic Fplc Image Manipulation Business Objects India Sirna/shrna Mediated Gene Silencing High Pressure Environments Vaccines Infection Transduction Diabetic Unified Communications Hybrid Systems Clinical Trials Southern Western Northern Cell Biology Pol In Vivo Ires Manuscript Immunology Seattle Virus Mediated Carcinogenesis Basic Sciences Induction Rna Isolation Epigenetic Analysis Disease Knock In Knock Out Transgenic Mouse Statistics Gene Expression Mechanism Of Action Studies Synthetic Clinical Practices Public Speaking Signal Genotyping Res Hplc Doi Photoshop Cell Virology Cho Titration Concept Generation Transient Patient Computer Literate Robust Rt Pcr Informatics Hepatocellular Carcinoma R&d Abstracts Cell Lines Signal Transduction Transfection Tk Upstream Assay Development Hbv Queries Molecular Genetics Software Lifecycle Dna Sequencing Genotype Assays For Transgenic/knock Out Mice Art Elisa Hev Confocal Microscopy Expression Grants Ich Guidelines Sci Clearance Dallas Wang Software Frame Bioassay Affinity Chromatography Biologics Serum Endocrinology Technical Proficiency Biosafety Scanners Summarize Meetings French Abstraction Insect

Santanu Raychaudhuri Education Details

  • Jadavpur University & Uconn Health Center
    Jadavpur University & Uconn Health Center
    Biochemistry And Molecular Biology
  • Uc San Diego
    Clinical Trial Management

Frequently Asked Questions about Santanu Raychaudhuri

What is Santanu Raychaudhuri's role at the current company?

Santanu Raychaudhuri's current role is Principal Investigator & Senior Scientist.

What is Santanu Raychaudhuri's email address?

Santanu Raychaudhuri's email address is s_****@****hoo.com

What is Santanu Raychaudhuri's direct phone number?

Santanu Raychaudhuri's direct phone number is +142424*****

What schools did Santanu Raychaudhuri attend?

Santanu Raychaudhuri attended Jadavpur University & Uconn Health Center, Uc San Diego.

What skills is Santanu Raychaudhuri known for?

Santanu Raychaudhuri has skills like Chromatography, Qpcr, Dna And Rna, Molecular Virology, Cap, Fungal, Highly Focused, Undergraduate, Knock Outs, Slides, Infectious Diseases, Students.

Not the Santanu Raychaudhuri you were looking for?

Free Chrome Extension

Find emails, phones & company data instantly

Find verified emails from LinkedIn profiles
Get direct phone numbers & mobile contacts
Access company data & employee information
Works directly on LinkedIn - no copy/paste needed
Get Chrome Extension - Free

Download 750 million emails and 100 million phone numbers

Access emails and phone numbers of over 750 million business users. Instantly download verified profiles using 20+ filters, including location, job title, company, function, and industry.