Sarah Withey Email & Phone Number

United Kingdom

Belmont, Ma, Us

Boston, Ma, Us

Instructor in Psychiatry at Harvard Medical School, Assistant Psychobiologist at McLean Hospital

Boston, Ma, Us

Bristol, Gb

Developing effective pharmacological online tools for science, medical and dental undergraduate students.

Bristol, Gb

Thesis entitled ‘The Mechanisms of Opioid Tolerance’.My thesis focused on the involvement of protein kinase C (PKC) in the development and maintenance of opioid induced tolerance by looking at acute desensitisation, cellular tolerance, respiratory depression and locomotor activity. Interestingly, opioid tolerance has previously been shown to be reversed by low concentrations of ethanol and it has been postulated that PKC may play a role in this potentially lethal interaction.Throughout my PhD I developed expertise in a variety of fields including pharmacology, electrophysiology, behavioral techniques and neuroscience. Specific skills and techniques include: opioid receptor pharmacology, patch clamp electrophysiology, in vivo biology, whole animal plethysmography, locomotor activity, confocal microscopy, tissue culture and western blotting.

Bristol, Gb

Teaching (Inc. one to one tutoring): Pharmacology, medical science, anatomy and dentistry

Cardiff, Gb

Ensuring that clinical trials are set-up, approved by the R&D office and conducted in accordance with the Research Governance Framework for Health and Social Care in Wales. Understanding and application of GCP and GMP in accordance with MHRA, FDA and EMA regulations and guidelines.Assisting in the review of contracts: identifying changes to model clinical trial agreements and assisting in assessment of the appropriateness of contracts for the clinical trial. Assumed a lead role in the administrative element of the contracting process.Liasing with commercial and non-commercial finance departments to ensure timely invoicing of the organisation.Development and management of local information systems and liaising with the R&D Clinical Board Leads as appropriateAssisting in monitoring and maintenance of protocol and ICH-GCP adherence on-siteProviding assistance to the R&D managers and directors in producing annual reports, annual plans and other departmental documents and presentations as required.Communication with various stakeholders both internal and external to the Cardiff and Vale Health Board in dealing with general R&D queries

London, England, Gb

Key role: Developing/funding outreach events for a variety of audiences. Collaborators include: Science museum (London), Techniquest (Cardiff) and @Bristol (Bristol).

Auxillary nurse for the Blaenau Gwent nurse bank

Enterprise competition involving setup of a pharmaceutical company based upon a novel pharmaceutical idea. This accumulated in four days of developing a business plan which was presented to, and scrutinised by, venture capitalists. Topics of workshops included: The Requirements of a Business Plan, Intellectual Property and Patenting Strategy, Regulatory affairs, Raising and Managing Finance & Commercial and Marketing Strategies. [Stevenage, UK. GSK, MRC, BBSRC sponsored]

Brentford, Middlesex, Gb

Worked as an in vitro scientist at the GSK Clinical Imaging Centre. Research roles included assessing the potential alterations in binding properties of radiotracers commonly used in human PET imaging following cellular regulatory mechanisms such as internalisation. Also provided assistance in pre-clinical imaging studies utilising PET and MRI techniques and in clinical MRI imaging studies run at the Cardiff University Brain Research Imaging Centre, CUBRIC, in collaboration with Imperial College London.

Doctor Of Philosophy (Phd), Pharmacology

Biomedical Science (Anatomy), Biomedical Sciences, General