Sean Black Email & Phone Number

Clarksburg, Md, Us

United States

Led end-to-end transformation of a partial web application into a production-ready SaaS platform at bitformance.com. Rebuilt the Flask API backend with improved scalability while developing automated processing frameworks using AWS EC2 and cron jobs. Engineered efficient proprietary algorithms and implemented dual-database architecture using PostgreSQL and MongoDB.Managed comprehensive cloud infrastructure on AWS and spearheaded React frontend development, integrating new features with the optimized backend. Configured NGINX servers, handled domain management, and maintained Git repositories for seamless deployment and version control. Successfully reduced technical debt while preserving and enhancing critical system functionality.

Rockville, Maryland

Optimized and modernized bioinformatics pipelines using Polars Python framework, achieving 10x improvements in both memory efficiency and processing speed for long-read sequencing QC. Developed comprehensive NGS data analysis workflows leveraging SLURM clusters for parallel processing, while building full-stack web applications that enable intuitive QC metric visualization for lab managers.Created and enhanced genomic analysis infrastructure through custom data pipelines, PostgreSQL schemas, and integration of industry-standard tools like GATK and DeepVariant for Oxford Nanopore Technologies platform. Automated complex bioinformatics workflows using Python, R, Perl, and Bash, significantly reducing manual workload while maintaining high standards of data integrity through rigorous validation protocols.

Gaithersburg, Md

Lead technical operations for Hamilton STAR/STARlet and Perkin Elmer Sciclone/Zephyr automated liquid handling systems at GeneDx. Provide comprehensive hardware/software support while developing and optimizing automated protocols for high-throughput laboratory testing. Successfully designed and implemented two Hamilton-based automation solutions for sample processing, enabling precise dilution tracking and PCR setup for spectroscopy and sequencing analysis. Manage preventive maintenance schedules and new protocol deployments to ensure continuous laboratory operations.

Gaithersburg, Maryland

Specialized in high-throughput genetic testing, executing both automated and manual PCR analysis for hereditary disorder screening. Process hundreds of clinical samples daily using advanced DNA amplification techniques, generating crucial genetic data for disease identification. Collaborate with senior scientists to deliver actionable genetic insights that directly inform patient diagnosis and treatment plans.

123 Engel Hall, Virginia Tech, Blacksburg, Va 24060

My responsibilities included extracting and isolating DNA from cultures of methanoarchaea and bovine rumen contents. I have researched protocol for the cultivation of rumen ciliate Protozoa and Acidobacterium found in soil and have determined gene sequences for polysaccharide biosynthesis within Acidobacterium while designing primers for those sequences. I have also tested metagenomic DNA from various soil samples for components of an antibiotic resistance cassette (developed by faculty at Virginia Tech Carillion School of Medicine) by PCR analysis. Other responsibilities included preparing stock solutions and reagents, autoclaving and sterilization of lab equipment, and maintaining a clean and well organized laboratory environment.

Led a five member academic committee while designing an internal tutoring system and organizing study hour session. This resulted in upholding the minimum average GPA requirement for 70 members.

Johnston Student Center, Virginia Tech

As an assistant manager, it was my responsibility to aid the store manager in the effective and successful running of the Johnston Student Center Subway. I was responsible for taking inventory and balancing cash registers by utilizing a P.O.S. based system, as well as making bank deposits of daily revenue. I was responsible for receiving and verifying deliveries of shop supplies as well as ensuring that proper sanitation and cleanliness was kept throughout the shop. I was also responsible for training new employees on basic shop operations.

Summit, Nj

As a paralegal assistant I was responsible for analyzing client information and putting that information into a software database known as "ProLaw". I also contributed to the successful filing of provisional patent applications by numbering the figures and drawings in each application by using Microsoft Publisher. I have also compiled, organized, and made several copies of individual client files to reference for future use.

Master'S Degree, Bioinformatics

Graduate of the MS in Bioinformatics program at JHU. Proficient in Java, Python, Perl, HTML, CSS, bash scripting with the linux.

Bachelor Of Science - Bs, Biochemistry