Seth Andrews Email & Phone Number

Cary, Nc, Us

Durham, North Carolina, United States

Acting Process Development team lead during acquisition and transfer of cell therapy asset from Precision Biosciences to Imugene. Supervised and assisted with multiple business activities to ensure successful transfer, requiring cross-functional and inter-organization collaboration. Prioritized and ensured continuity of key activities during transition.

Durham, North Carolina, United States

Senior member of Process Development team for clinical stage allogeneic CAR T cell therapy. Supported successful technology transfer as PD representative. Supervised junior engineers in continuous improvement and risk mitigation projects.

Assisted in the development of a clinical stage cell therapy manufacturing process. Evaluated, optimized, and integrated a cell processing device to improve recovery and processing times while reducing risk.

Serve as senior researcher in NSF-supported academic laboratory investigating mesenchymal stromal cell (MSC) manufacture and potency and developing immune suppression assays of MSC secretome.• Plan and conduct cell biology experiments, analyze data, and develop response to findings.• Prepare presentations describing scientific results and progress for department meetings; present findings to department and at professional meetings. Write and submit articles on studies to peer-reviewed journals.• Provide overall leadership to lab, supervising 6 undergraduate and graduate students to include coordinating work, training, and serving as mentor.

Athens, Georgia Area

Investigated manipulation of MSCs by genetic and physiochemical means to improve their therapeutic potency, as part of this academic laboratory funded by NIH, DARPA, and NSF.• Tripled yield and doubled therapeutic potency of stem-cell-derived extracellular vesicles by introducing cost-efficient physiochemical cues.• Collaborated across 3 labs and 2 universities to investigate effect of BMP-2 transduced mesenchymal stem cells on bone regeneration, including in vitro release kinetics and in vivo effectiveness in long-bone defect models.• Developed/delivered presentations for internal/external meetings. Wrote articles for peer-reviewed journals.

Athens, Georgia Area

Assisted with characterization and quality checks of functional protein product at this biotech startup.• Optimized functional assay for chemokine product.• Designed experiments to study release kinetics of chemokine from orthopedic tissues and in vivo effectiveness for immune masking of allogeneic tissues based on input from senior scientists and clinicians.

Hershey, Pa

Served as mid-level researcher and engineer in clinician-facing orthopedics laboratory within major academic hospital.• Collaborated with surgeons, scientists, and engineers to design and execute clinical studies in biomechanics.• Co-wrote and awarded $50,000 grant from Clinical and Translational Science Institute.

Developed system for design/testing of orthopedic implants for project sponsored by leading medical device company. • Assessed needs of project sponsor (Stryker) and developed required specifications.• Designed in vitro synthetic bone analogue that accurately modeled bone geometry and mechanical properties.• Wrote and presented final design report to sponsor stakeholders.

Investigate possible genotypic difference between different Giardia morphologies

Determine the effect of hyaluronan in solution for preventing apoptosis of intramuscularly injected stem cells

Doctor Of Philosophy (Ph.D.), Biological Engineering

Master Of Engineering (M.Eng.), Biomedical/Medical Engineering

Bachelor Of Science, Biological Engineering

Activities and Societies: Alpha Zeta