Associate Scientist
CurrentI work with the Organ Manufacturing Group at United Therapeutics on their effort to develop bio-compatible 3D-printed scaffolds for whole organ bio-printing. Specifically, I:• Design and develop mechanical characterization techniques for our candidate biomaterials• Test native tissue to develop our understanding of native biomechanics and inform our mechanical testing targets• Work with a range of internal teams to help develop formulation and print parameters leading to more physiological mechanics of candidate biomaterialsThus far, I have:• Incorporated native lung dissection and testing strongly into our goal-setting approach so that mechanical testing targets are obtained in a data-driven manner that is sensitive to the vast mechanical heterogeneity of the native organ• Personally performed dissection and testing of native porcine lungs to extract and test branching sections of native airway and vasculature. These test results were used to develop a localized map of mechanical properties of the different constituent tissues of the lung• Redesigned the organizations' mechanical testing protocols to comply with testing standards (specifically, ASTM D638 and ISO7198) where applicable, while adding extra layers of rigor such as fluid bath testing and specimen visual analysis to ensure physiological relevance• Developed and incorporated dynamic testing capabilities via viscoelasticity and fatigue testing protocols, with custom-designed fixtures for multi-specimen testing to increase throughput• Collaborated with multiple working groups at the company to a) disseminate information about mechanical testing and native biomechanics, b) perform personnel training on mechanical testing protocols, and c) organize goal-setting discussions to obtain perspective and buy-in from these groups.