Stanislav Nagy Email & Phone Number

Copenhagen, Dk

Hørsholm Municipality, Capital Region Of Denmark, Denmark

Copenhagen, Capital Region, Denmark

Designed, planned and executed a multidimentional genetic screen using Drosophila melanogaster. Using RNAi, we screened >200 secreted factors and transmembrane sensing proteins, specifically in secretory cells of the gut, and assayed their role in regulating a range of systems. The collective phenotypic space included measurements of survival under stress (nutrient, osmotic, and oxidative), levels of stored nutrients (lipids and sugars) under homeostatic and starvation conditions, fecundity… Show more Designed, planned and executed a multidimentional genetic screen using Drosophila melanogaster. Using RNAi, we screened >200 secreted factors and transmembrane sensing proteins, specifically in secretory cells of the gut, and assayed their role in regulating a range of systems. The collective phenotypic space included measurements of survival under stress (nutrient, osmotic, and oxidative), levels of stored nutrients (lipids and sugars) under homeostatic and starvation conditions, fecundity (their ability to reproduce), as well as sleep and feeding behaviors. The goal was to discover novel targets involved in the gut's role to affect a range of peripheral systems and animal homeostasis. Currently I’m developing an analytical approach to better leverage this multi-parameter dataset to describe potential phenotypic spaces and understand the interaction between metabolism, stress tolerance, fecundity and behavior. Show less

Copenhagen, Capital Region, Denmark

Studying molecular mechanisms of inter-organ communication to maintain metabolic homeostasis in response to nutritional and environmental conditions using Drosophila melanogaster.

Department Of Biology.

Using Drosophila as a model organism for research in neuropsychiatric disorders, the impact of environment on development, metabolism and organ growth and interorgan communication. Implementing and developing a variety of biological experimental techniques, microscopy and image analysis.Established techniques to study behavior in Drosophila melanogaster. Implemented germ-free animals to study the role of bacteria on development and behavior. Studied the signals that coordinate organ and… Show more Using Drosophila as a model organism for research in neuropsychiatric disorders, the impact of environment on development, metabolism and organ growth and interorgan communication. Implementing and developing a variety of biological experimental techniques, microscopy and image analysis.Established techniques to study behavior in Drosophila melanogaster. Implemented germ-free animals to study the role of bacteria on development and behavior. Studied the signals that coordinate organ and animal growth. Developed quantitative analysis tools for data obtained with confocal microscopy. This work was independently funded by Danish Research Council MOBILEX grant (2.3 mil DKK) “A novel approach to uncover the principles of mind-altering microorganisms” Show less

University Of Chicago

Postdoctoral fellow in the lab of David Biron. My focus was 1. characterizing mechanisms that regulate quiescence behavior in the nematode C. elegans and 2. development of high temporal and spacial quantitative behavioral analysis of C. elegans behavior with the aim of understanding the modulation, maintenance and regulation of locomotive patterns on developmental and immediate timescales.

Phd, Biophysics

I worked with Dr. Ronald S. Rock. For my doctoral thesis project I focused on the molecular mechanism of Myosin X, a molecular motor.

Bs, Biochemistry