Study DirectorStudy director for GLP and non-GLP in vitro chromosome aberration (human peripheral lymphocytes) and in vitro micronucleus (MN) assays (human peripheral lymphocytes and CHO-K1 cells):•Scheduling of studies.•Protocol compilation.•Determination of testing parameters. •Report compilation. •Communication of test results and issues with the sponsor. •Managing timelines for studies. •Collectively working with report writers and quality assurance.•Quality check of all study records and data.Study MonitorStudy monitor for in vitro skin sensitization assays. Task includes scheduling of studies with CROs. Reviewing and approving protocols, data, and report. Communication of assay results with toxicologist. Lead TechnicianLead technician for GLP and non-GLP in vitro chromosome aberration assays, in vitro MN assays, in vivo MN assays and in vitro mouse hepatocyte proliferation assay: •Study notebook compilation.•Conducting assays.•Analyzing assays.•Helping to set up study designs. •Providing technical input.•Communicating with the study director as needed. •Organizing data. Methods DevelopmentCompleted methods development for the in vitro MN assay, which resulted in a GLP business offering and the MLA and hepatocyte proliferation assay:•Literature review in order to design experiments.•Protocol design and compilation.•SOP compilation.•Report compilation.•Study record compilation.•Successfully conducting assays.•Assay analysis:Flow cytometer analysis (MN)Colony counting in microplates (mouse lymphoma)Fluorescent microscopy (hepatocyte proliferation, in vitro MN)•Establishing historical control data.•Performing statistical analysis. •Training and directing junior technicians. •Working with senior staff to develop additional testing parameters. Additional Skills•Flow analysis of in vitro and in vivo MN samples.•Preparation and fluorescent microscopy of bone marrow MN slides.•Preparation of samples for QPCR.

Study DirectorStudy director for GLP and non-GLP in vitro chromosome aberration and in vitro micronucleus assays:•Scheduling of studies.•Protocol compilation.•Determination of testing parameters. •Report compilation. •Communication of test results and issues with the sponsor. •Managing timelines for studies. •Collectively working with report writers and quality assurance.•Quality check of all study records and data.Lead TechnicianLead technician for GLP and non-GLP in vitro chromosome aberration assays, in vitro micronucleus assays, in vivo micronucleus assays and in vitro mouse hepatocyte proliferation assay: •Study notebook compilation.•Conducting assays.•Analyzing assays.•Helping to set up study designs. •Providing technical input to ensure that the assays are being conducted in the most efficient manner. •Communicating with the study director as needed. •Organizing data. Methods DevelopmentCompleted methods development for the in vitro micronucleus assay, which resulted in a GLP business offering and the mouse lymphoma assay and hepatocyte proliferation assay:•Literature review in order to design experiments.•Protocol design and compilation.•SOP compilation.•Report compilation.•Study record compilation.•Successfully conducting assays.•Assay analysis:Flow cytometer analysis (micronucleus)Colony counting in microplates (mouse lymphoma)Fluorescent microscopy (hepatocyte proliferation)•Establishing historical control data.•Performing statistical analysis. •Training and directing junior technicians who assist with the methods development. •Working with senior staff to develop additional testing parameters. Additional Skills•Flow analysis of in vitro and in vivo micronucleus samples.•Preparation of bone marrow micronucleus slides.•Fluorescent microscopic analysis of bone marrow micronucleus slides.•Preparation of samples for QPCR and conducting QPCR.

BSL-2 and BSL-3 LaboratoryMicrobiologyMicrobiological organisms: B. anthracis, B. anthracis Sterne, B. cereus, B. atrophaeus, Y. pestis, F. tularensis, Brucella suis, Brucella abortus, B. mallei, B. psuedomallei, Shigella sonnei, salmonella species, bacillus species, Escheria coli, Psuedomonas aeruginosa, Staphylococcus aureus• Microbiological decontamination and persistence monitoring • Microbiological techniques (streaking plates, inoculating broths, glycerol stocks)• EPA Decontamination tests (AOAC method, modified Three Step Method, Quantitative Carrier Test, iSOP) and internal decontamination tests• Laser-Induced Breakdown Spectroscopy (LIBS)• Designed and developed bacteriophage assayMolecular/Cell Biology/ Immunology• Routine cell culture maintenance for adherent and suspension cells • Toxin Neutralization Assays and Toxin Potency Assays• Real-Time Polymerase Chain Reaction (ABI 7000 and Lightcycler)• Enzyme Linked Immunosorbent Assays (ELISA) General• Responsible for new employee training• Assisting with costing and other project management tasks • Technical writing (SOP, method, and form development)