Stephen Claridge Email & Phone Number

Montreal, Quebec, Canada

Montreal, Quebec, Canada

Design and synthesis of novel 25-hydroxychlolesterol analogues. Design and synthesis of novel CDK12 inhibitors. Synthesis of molecules on a fee-for-service basis. Mentored 1 scientist.

Montreal, Canada Area

Design and synthesis of novel small molecule PROTACs. Parallel synthesis of peptides from resin supported amino acids. Scale up of a molecule for non-GMP preclinical studies, delivered 200 g. Synthesis of novel small molecules for oncology.

Montreal, Canada Area

Design and synthesis of novel small molecules for use in oncology based upon thalidomide. Design and synthesis of novel bromodomain inhibitors. Design and synthesis of RAK inhibitors. Design and synthesis of HIF inhibitors. Synthesis of molecules on a fee-for-service basis. Mentored 2 associate scientists.

Montreal, Canada Area

Scale up of HDAC inhibitor for non-GMP preclinical studies (100 g scale).

Montreal, Canada Area

Supervised students in CEGEP chemistry labs.

Montreal, Canada Area

Synthesis of novel compounds for use in sunscreens.

Montreal, Canada Area

Design and synthesis of novel VEGRF-2, FAK kinase inhibitors. Synthesis of novel nucleobase analogues. Supervised 2 direct reports.

Montreal, Canada Area

Design and synthesis of novel c-Met, VEGFR-2, AXL kinase inhibitors. Co-inventor of 2 clinical candidates, Glesatinib and Sitravatinib. Supervised 2 direct reports.

Montreal, Canada Area

Design and synthesis of beta-lactamase inhibitors. Design and synthesis of analogues of s-adenosyl-l-methionine as DNA methyltransferase inhibitors. Design and synthesis of HSP90 inhibitors. Safety committee member. Supervised 1 direct report

Postdoctoral Reseach, Organic Synthesis

Total synthesis of a novel inhibitor of Renin (in collaboration with Novartis) Synthesis of methanoproline analogues using a Simmons-Smith.

Doctor Of Philosophy - Phd, Organic Synthesis

Synthesis of novel fused ring carbocycles using an intramolecular Nicholas reaction in the key cyclisation step. Synthesis of novel.

Bachelor Of Applied Chemistry, First Class (Honours)

Co-op year at Kodak UK, carrying out the synthesis of novel molecules for use in photographic films.