Stephen Abbott Email & Phone Number

Cambridge, MA

Waltham, MA

• Responsible for development of study proposals and execution of in-vivo tolerability, PD/PK, efficacy, modeling studies, animal ordering, injections (sc, ip, iv, id), tissue/blood collection for analysis, measurements.
• Assist with cell culture harvesting, scale-ups for mammalian cell lines to be dosed in-vitro
• Provide guidance, data updates, recommendations, and future study proposals as a Pharmacology project team lead

Cambridge, Massachusetts

• Study Director for all aspects of in-life experiments (Protocol creation, animal ordering, cell culture, injections, measurements, data compilation, presentation and interpretation)
• Develop more efficient operating procedures to coincide with rapid company growth and a larger study output demand
• Technical training and development of new and junior associates
• Routine culture and maintenance of cell lines for various mouse tumor models
• Establish xenogeneic mouse tumor models and murine stem cell engraftment models
• Routine injections (sc, ip, iv, id), measurement of tumors, necropsy, blood and tissue collection for in vitro assays, monitoring of animal health, mouse handling, etc.

Lexington, MA

• Liaise outsourced studies through CROs, and prepare and review scope of work documentation
• Assist with development and characterization of complex disease models to evaluate therapeutic efficacy of drug candidates
• Contribute to the discovery and validation of new target opportunities for drug development
• Perform specialized in-vivo imaging techniques to accelerate development timelines and improve clinical translatability
• Assist with the creation of protocols, study designs, and SOP documents
• Processing, compilation, and reporting of data/study results to scientific staff

Lexington, MA

• Provide advanced technical support for Principal Investigators to ongoing research programs (imaging, dose administration, necropsies, blood collection/processing, tissue harvests, assays)
• Manage procurement of laboratory supplies within the research facility
• Supervise and train lab technicians on study procedures and technical work
• Manage all in-house animal colonies - ordering, census database, weaning, identification, biopsies, and shipments to CROs
• Ensure compliance of regulations and guidelines for company policies and practices onanimal care and research security (GLP, USDA, AWA, OSHA, IACUC)
• Review and implement new SOPs to coincide with facility requirements

• Maintain all project breeding colonies - genotyping, biopsies, weanings, and census reporting
• Primary technical support to the scientific staff
• Perform animal husbandry duties including cage changing, observation, treatment, vivarium maintenance and general housekeeping per Standard Operating Procedures
• Monitor and manage the procurement of facility supplies

Sitka, Alaska

• Assist Veterinarian with clinic procedures (blood drawing, physical examinations, anesthesia, euthanasia, x-ray imaging, animal restraint, behavior observation and recording)
• Manage animal husbandry staff and volunteers
• Social media development specialist
• Train and handle new raptors for residence at the center
• Deliver formal education programs for a variety of audiences (pre-school through adults)
• Perform animal husbandry duties (sanitizing enclosures, building new habitats, preparing diets)

Los Angeles

• Oversight of the breeding colonies
• Maintain census, data logs, and spreadsheets
• Promptly complete Animal Release Requests for laboratory PI
• Collaborate with fellow colleagues to ensure completion of daily tasks
• Evaluate animal health, report abnormal conditions, monitor and provide treatments as directed

• Oversight of the in-house breeding colonies and genotyping services
• Document, organize, and maintain timely records for activities
• Provide guidance and training to less experienced staff and student interns
• Quality Assurance primary for the vivarium equipment calibration program
• Evaluate animal health, report abnormal conditions, monitor and provide clinical treatments
• Complete animal husbandry and support services according to SOPs