Steve Collier Email & Phone Number

Concord, MA, US

Cambridge, MA, US

Cambridge, MA, US

Cambridge, MA, US

Leadership of Drug Substance Process Development and Drug Substance and Drug Product Analytical Development functions in Technical Operations covering later stage and commercial portfolio from bulk raw materials to micronized API. Oversight of CMC Project Leads for later phase developmental candidates.Project responsibilities include:- Brexanolone.

Cambridge, MA, US

Leadership of drug substance process development function in Technical Operations (including Sage employees and external consultants) covering late stage and commercial API portfolio from bulk raw materials to micronized API including:- Brexanolone (SAGE-547): approved for treatment of post-partum depression (PPD)- Zuranolone (SAGE-217): in Phase 3 trials.

London, Greater London, GB

Leadership of all R&D operations at JMPS, a leading API CDMO. Activities include contract research, custom synthesis, analytical and process development, scale up, optimization and manufacturing from preclinical to fully commercial APIs. Responsibilities included:- Overall line management of >100 scientists and technicians from groups including: chemical.

London, Greater London, GB

Leadership of all R&D and manufacturing operations at JMPS, including two pilot plant facilities. Role similar to that above with additional manufacturing responsibilities including: - Led all GMP pilot plant manufacturing operations at JMPS including two pilot plant facilities with 5 reactor trains ranging from 200 gal to 750 gal reactors and two process.

Singapore, Singapore, SG

Redwood City, CA, US

• Site manager and leader of a multi-cultural team of up to ~45 R&D plus support staff, spanning disciplines including process R&D, molecular biology, analytical biochemistry, analytical development, bioinformatics.
• Site GM for ~3 years, member of the Board of Directors and key interface with Singapore Economic Development Board.
• Accountable for Codexis Pharma R&D, delivering client-facing and internal projects to develop engineered industrial enzymes and associated processes, for applications in pharma inters and APIs.
• Responsible for development of part of Codexis’ CodeXyme cellulase portfolio for biomass saccharification. Included: process development, optimization of the package and evolution of cellulytic enzymes.
• Built a research culture rich in customer and results focus and project management discipline, ensuring on time and to spec delivery of projects.
• Created a highly flexible, cross-trained R&D organization able to adapt to changing business needs and project types from rapid response screens to long term research programs. Retasked parts of this unit to address.

Redwood City, CA, US

• Led a team of process development chemists working on interdisciplinary projects leveraging engineered enzymes to target green and sustainable manufacturing routes to pharmaceutical intermediates and APIs, including.
• Responsible for recruitment, training and performance management of team.
• Built a culture of robust process design and development, introducing process envelope studies, application of DOE and reaction screening and completely overhauling the tech transfer process.
• Numerous successful tech transfers to clients globally.

Albany, NY, US

• One of a 4-person team selected to set up and run AMRI’s Singapore site; led a team of up to 17 scientists.
• Trained and managed new recruits to work on client facing projects including: custom synthesis, medicinal chemistry, agrochemicals, library synthesis and process development, from mg to kg scale.
• Heavily involved in bid preparation following client requests for proposals, with some experience in business development
• Involved in design/set up of the facilities and equipping the laboratories.
• Built strong, trusting relationships with clients, with frequent written and verbal communication.

Albany, NY, US

• Senior Research Scientist (SRS) to SRS IIDesign and development of safe, robust and scalable processes to APIs including generics, for both external customers (pharma, biotech) and internal clients.
• Project, team and customer management.
• Route design and selection, process development, optimization, scale up, and tech transfer to a GMP kilo lab or pilot plant facilities.
• Thought-leader in the implementation of advanced techniques including Design of Experiment (DOE) studies, parallel reaction screening (RS10, Multimax) and RC1 hazard evaluation.

Senior Scientist to Project Team LeaderScientific, project & team leadership, and customer management on complex custom synthesis, and process development projects including mg to multi kg scale, cGMP, pharmaceutical actives, intermediates, controlled substances and agrochemicals.

Brentford, Middlesex, GB

Agency contract positionLab scale synthesis, use tests and impurity synthesis, under cGMP conditions.

Agency contract positonEarly lead support for agrochemicals process development including route design and lab scale synthesis

Johnson Matthey Senior Leaders Program, Organizational Leadership And Strategy

Phd, Organic Chemistry

Bsc (Hons), Chemistry With Industrial Chemistry