Katherine Tan Email & Phone Number

Champaign, Illinois, United States

• Leading a collaboration with an international pharmaceutical company to develop a disease modifying treatment for Huntington’s Disease (HD), using CRISPR-Cas gene editing technology. Involves early R&D (molecular biology), in vitro studies in human cell lines, HD mouse models, and larger animal models. • Mentoring, teaching, and managing 5 undergraduate research assistants. • Applying conditionally controlled optogenetic and small molecule domains to CRISPR systems.• Increasing the safety of genome editing technologies.• Developing unbiased CRISPR off-target detection methods that increase ease of implementation while decreasing cost compared to current methods.

Champaign, Illinois, United States

For Bioengineering Senior Design Capstone course:• Guided biweekly team meetings to provide project guidance, and review progress of deliverables.• Facilitated discussion to refine project objectives according to sponsor requests and student expertise. • Grading of posters and extensive written deliverables.

Champaign, Illinois, United States

Operated and optimized a 300+ member organization with a 12-member senior leadership team. Oversaw 3 managers and 24 consultants to complete 3 projects in 12 weeks.

Champaign, Illinois, United States

Led economic feasibility analysis of a $45 million asset. Delivered successful VC investment pitch showing $88 million NPV, with go-to-market strategy, carbon neutral strategy, and potential partnership for 75% reduced time to market, and 98% reduced initial investment.

Champaign, Illinois, United States

Identified emerging markets for clean energy insurance underwriting, through evaluating loss data, government funding, industry risk frequency/severity, competitive landscape, and demand.

Lake Forest, Illinois, United States

• Developed Bio-layer Interferometry (BLI) bioassays for robust and precise analysis of biomolecular interaction binding kinetics/affinity between 5 different biopharmaceutical monoclonal antibodies and their physiological receptors/signaling molecules, with a 1 hour run time. • Reduced assay preparation time using automation technology.• Worked on using Surface Plasmon Resonance (SPR) to quantify the biomolecular interaction binding kinetics/affinity between monoclonal antibodies and a molecule within the human complement response.• Experiments performed according to GLP, documented using eLN systems• Wrote SOPs for developed methods according to the official Pfizer template.

Lake Forest, Illinois, United States

• Worked with Pfizer colleagues to develop and qualify analytical methods.

Austin, Texas, United States

• Worked on studying the mechanism of neural tube closure and its relation to neural tube defects• Used Microinjectors, Fluorescence Microscopy, and Tissue Analyzer to visualize and analyze Planar Cell Polarity (PCP) controlled Apical Constriction during Neural tube closure in X. Tropicalis.

Master Of Science - Ms, Biotechnology

Doctor Of Philosophy - Phd, Bioengineering

Bachelor'S Degree, Biochemistry

Activities and Societies: Texas China Care