For over 47 years, Fermentec has been at the forefront of developing and transferring cutting-edge technologies to sugar and ethanol plants, establishing itself as a cornerstone in the sugar and ethanol sector. In alignment with the Industry 4.0 concepts, Fermentec is ready to tackle the challenges of aligning digitization/digital thinking and efficiency improvement. Their objectives encompass:• Facilitate the transition of processes into Industry 4.0, embracing the latest technological… Show more For over 47 years, Fermentec has been at the forefront of developing and transferring cutting-edge technologies to sugar and ethanol plants, establishing itself as a cornerstone in the sugar and ethanol sector. In alignment with the Industry 4.0 concepts, Fermentec is ready to tackle the challenges of aligning digitization/digital thinking and efficiency improvement. Their objectives encompass:• Facilitate the transition of processes into Industry 4.0, embracing the latest technological advancements.• Conducting comprehensive analysis and interpretation of industrial data, elucidating variations and trends within ethanol and sugar production processes.• Facilitate the transition of processes into Industry 4.0, embracing the latest technological advancements.• Conducting comprehensive analysis and interpretation of industrial data, elucidating variations and trends within ethanol and sugar production processes.• Engagement in modeling and process optimization endeavors to enhance overall efficiency.• Pursuit of continuous improvement of processes and offering training programs grounded in Lean and Six Sigma concepts.• Intense search for innovative solutions with a substantial operational impact, strategically optimizing processes, reducing costs, and augmenting overall efficiency.Fermentec's commitment to these objectives positions the organization as a catalyst for transformative advancements in the evolving landscape of sugar and ethanol production. Show less

• Spearheaded the development of innovative control strategies for alcoholic fermentation at the bench-scale bioreactor.• Fostered collaboration with the CODES research group at West Virginia University, leveraging operability analysis and biomimetic algorithms to advance bioprocess optimization.• Achieved a substantial 25% increase in product yield and an impressive 50% reduction in process variability through the application of the proposed control framework.• Proposed… Show more • Spearheaded the development of innovative control strategies for alcoholic fermentation at the bench-scale bioreactor.• Fostered collaboration with the CODES research group at West Virginia University, leveraging operability analysis and biomimetic algorithms to advance bioprocess optimization.• Achieved a substantial 25% increase in product yield and an impressive 50% reduction in process variability through the application of the proposed control framework.• Proposed generation of artificial neural networks using genome-scale model data, enhancing predictive capabilities in the bioreactor control framework.• Successfully integrated the new artificial neural network with fuzzy models for a comprehensive and adaptive bioreactor control system.• Optimized upstream processes, including culture media optimization and reagent monitoring, contributing to overall efficiency.• Conducted downstream analyses, specifically HPLC analysis, and skillfully interpreted the data for meaningful insights.• Implemented thorough visualization and statistical evaluation of data using tools such as Origin and Minitab, ensuring robust analysis.• Demonstrated effective management of project resources, including material and equipment quotation.• Implemented 5S and Lean principles in laboratories, reducing waste and optimizing operational efficiency.• Reimplemented and managed Good Laboratory Practices (GLP) with a focus on biosafety manual adherence and material identification.• Contributed significantly to the scientific community with the publication of three manuscripts in high-impact journals.• Received recognition for project excellence and multidisciplinary teamwork at national congresses (COBEQ and Sinaferm), earning prestigious awards.• Invited to present at international congresses (BIOCON 2019), showcasing the project's global impact and significance Show less

• Led the development of a complex project within a highly multidisciplinary team, fostering collaboration across diverse expertise.• Integrated genome-scale models data (Optflux) into a bioreactor control framework (Labview), enhancing precision and control in the experimental setup.• Utilized databases such as KEGG and BRENDA to evaluate metabolic models, ensuring a comprehensive understanding of the underlying biological processes.• Applied surrogate models based on… Show more • Led the development of a complex project within a highly multidisciplinary team, fostering collaboration across diverse expertise.• Integrated genome-scale models data (Optflux) into a bioreactor control framework (Labview), enhancing precision and control in the experimental setup.• Utilized databases such as KEGG and BRENDA to evaluate metabolic models, ensuring a comprehensive understanding of the underlying biological processes.• Applied surrogate models based on simulated metabolic data to innovate novel process control strategies, resulting in a remarkable 25% increase in ethanol yield compared to alternative methods.• Conducted downstream analyses, including HPLC analysis, and employed statistical methods to validate the proposed process improvements.• Contributed significantly to the scientific community with the submission of two manuscripts to a high-impact journal, disseminating valuable findings.• Recognized for project excellence and multidisciplinary teamwork at a national congress (Sinaferm), receiving prestigious awards.• Received invitations to present and successfully presented at international congresses (BBEST and IBS 2018), showcasing the project's significance on a global stage. Show less

• Facilitated knowledge exchange with WVU's Control, Optimization, and Design of Energy Systems (CODES) group, fostering collaborative research efforts.• Conducted modeling, simulation, and computational parameter optimization for micro-aerated fermentation in batch bioreactors.• Integrated systems' biology (computational biology) into operability mapping and a predictive control framework, enhancing the understanding of complex biological processes.• Executed… Show more • Facilitated knowledge exchange with WVU's Control, Optimization, and Design of Energy Systems (CODES) group, fostering collaborative research efforts.• Conducted modeling, simulation, and computational parameter optimization for micro-aerated fermentation in batch bioreactors.• Integrated systems' biology (computational biology) into operability mapping and a predictive control framework, enhancing the understanding of complex biological processes.• Executed operability mapping for an alcoholic fermentation process, efficiently defining the operating region for optimal performance.• Successfully applied predictive control and a biomimetic algorithm through simulations, achieving improved alcoholic fermentation under micro-aerated conditions.• Significantly reduced process variability by addressing various sources of noise, including sensor noises accounting for up to 5% of deviation.• Simulations maintained micro-aerated conditions effectively, leading to an increased ethanol yield compared to a pure PID controller.• Submitted manuscripts documenting the research findings to a high-impact journal, contributing valuable insights to the scientific community. Show less

• Applied design of experiments (DOE) to systematically assess the impact of drying temperature (static drying) on the yield of citronella's essential oil, leading to the identification of optimal extraction conditions.• Investigated the influence of sample humidity on oil yield to understand the key factors affecting the extraction process.• Utilized Gas Chromatography-Mass Spectrometry (GC-MS) for comprehensive analysis of sample composition, providing insights into the… Show more • Applied design of experiments (DOE) to systematically assess the impact of drying temperature (static drying) on the yield of citronella's essential oil, leading to the identification of optimal extraction conditions.• Investigated the influence of sample humidity on oil yield to understand the key factors affecting the extraction process.• Utilized Gas Chromatography-Mass Spectrometry (GC-MS) for comprehensive analysis of sample composition, providing insights into the composition of each oil obtained and potential bioactivity.• Executed solid-liquid extraction of essential oil, employing hydrodistillation with the Clevenger apparatus.• Employed data visualization and statistical analysis tools (Origin and Statistica) through ANOVA to derive meaningful insights from the experimental data.• Successfully presented the project at a national congress (COBEQ), sharing valuable findings and contributing to the scientific discourse in the field. Show less

• Conducted analysis, study, and assurance of product quality throughout the beer and draft beer manufacturing process.• Applied physico-chemical, microbiological, and sensorial analyses for comprehensive quality assessment.• Utilized audit tools and quality tools to evaluate processes and data, contributing to continuous improvement.• Reviewed and re-implemented three Standard Operating Procedures (SOPs) related to the bottle sorting machine, bottle washing machine, and… Show more • Conducted analysis, study, and assurance of product quality throughout the beer and draft beer manufacturing process.• Applied physico-chemical, microbiological, and sensorial analyses for comprehensive quality assessment.• Utilized audit tools and quality tools to evaluate processes and data, contributing to continuous improvement.• Reviewed and re-implemented three Standard Operating Procedures (SOPs) related to the bottle sorting machine, bottle washing machine, and beer filling machine.• Ensured compliance with ISO and OSHA standards, overseeing material addressing, material labeling, and consistently updating macro spreadsheets for meticulous record-keeping. Show less

• Conducted a thorough assessment of antioxidant activity and performed phytochemical analysis on plant extracts from the genus Aniba.• Developed Standard Operating Procedures (SOP) for the production of plant extracts, utilizing techniques such as organic extraction and rotary evaporator.• Executed analytical and quantitative analyses of antioxidant activity, including DPPH assays with a comparison to ascorbic acid as a standard.• Conducted qualitative analysis of… Show more • Conducted a thorough assessment of antioxidant activity and performed phytochemical analysis on plant extracts from the genus Aniba.• Developed Standard Operating Procedures (SOP) for the production of plant extracts, utilizing techniques such as organic extraction and rotary evaporator.• Executed analytical and quantitative analyses of antioxidant activity, including DPPH assays with a comparison to ascorbic acid as a standard.• Conducted qualitative analysis of extract components, specifically identifying the presence of alkaloids and steroids.• Utilized data visualization and statistical tools (Origin and Statistica) with ANOVA to validate optimal conditions for extraction and determine the minimum concentration required for antioxidant activity.• Constructed standard models and adjusted models as necessary using Origin.• Identified promising antioxidant activity in the extracts, suggesting potential use as a component in future cosmetics formulations.• Presented the project at a national congress (COBEQ), showcasing the significant findings and contributions to the scientific community.). Show less

• Conducted comprehensive assessment of antifungal properties in Aniba roseadora's pure essential oil and emulsion (oil+emulsifier).• Executed experiments to evaluate vapor-phase inhibition power using Petri dishes and filters.• Utilized Gas Chromatography-Mass Spectrometry (GC-MS) for detailed analysis of sample composition, identifying biomolecules with heightened antifungal activity.• Applied Design of Experiments (DOE) to determine optimal conditions for solid-liquid… Show more • Conducted comprehensive assessment of antifungal properties in Aniba roseadora's pure essential oil and emulsion (oil+emulsifier).• Executed experiments to evaluate vapor-phase inhibition power using Petri dishes and filters.• Utilized Gas Chromatography-Mass Spectrometry (GC-MS) for detailed analysis of sample composition, identifying biomolecules with heightened antifungal activity.• Applied Design of Experiments (DOE) to determine optimal conditions for solid-liquid extraction of essential oil, employing hydrodistillation with Clevenger apparatus.• Employed data visualization and statistical analysis tools (Origin and Statistica) along with ANOVA to validate the best conditions and emulsion proportions.• Demonstrated complete inhibition using both pure oil and vapor methods.• Observed promising formation inhibition halos on solid media by employing emulsions with low concentrations of oil. Show less