Thierry Viard Email & Phone Number

Brisbane, California, Us

8 FTEs.- Collaborations & Research Studies Stewardship.- Research Partnership Studies- Execute, schedule, manage and perform sample processing in accordance with contractual obligations- Build Operational Excellence/Quality capabilities- GLP implementation and compliance- Technology Transfer

Brisbane, California, Us

4 FTEs.- Transplant Surveillance Products Research, Development and Validation, - Technology Support and Applications.- Technical Documentation and Regulatory support for IVDR submissions

Brisbane, California, Us

7 FTEs.Laboratory Products Development, Improvement, Support and Applications. Research and Clinical Studies Support and Management.Infectious Diseases Solutions Research and Development.

Brisbane, California, Us

4 FTEs.Research and Development, Product Development, Product Improvement, Project Management. - Manage the Laboratory Products Development Group.. - Launched AlloSeq cfDNA, a NGS-based kit for solid organ post-transplantation monitoring, as RUO and CE-IVD marked products.- Launched AlloSeq HCT, a NGS-based kit for genetic chimerism testing in Hematopoietic Cell Transplant (HCT) recipients.- Provided all validation studies and documentation required notably for CE-IVD qualification. - Customer and quality investigations support.- External Collaborations / Studies support and management. Poster and Oral presentations at relevant conferences.

Waltham, Ma, Us

5 FTEs.Research and Development Manager, Transplant Diagnostics Business.Product Development and Improvement for LinkSeq products post acquisition.

South San Francisco, Ca, Us

5 FTEs.Research and Product Development, Product Improvement, Project Management and Transfer of products from R&D to Manufacturing.- Managed the R&D group. - Launched several qPCR-based IVD genotyping kits related to HLA typing and blood typing and improved more than 150 existing qPCR based typing assays, notably developing and implementing Probes-free Real-Time multiplexed assays.- Provided all validation studies and documentation required notably for CE-IVD qualification and 510k submission. - New materials validation and second vendors qualifications.- Customer and quality investigations support.

Hercules, Ca, Us

Transfer of a $14 Million Product Line to the US.- Designed new processes (from raw materials to automated dispensing systems for finished goods) to integrate technical specificities of the current products into in-place workflows. - Maintained AFNOR, AOAC and Health Canada certifications after transfer completion.- Coordinated resources from various different key functional groups, located in France or in the US, including R&D, QA, QC, Production, Finance, Process Development, Packaging, Material Management, Supply Chain, Planning, Distribution, Project Management and Marketing, resulting in the successful transfer of 22 different formulations, securing 90% of the business in less than 6 months.

Hercules, Ca, Us

Process Development, Transfers Optimization and Manufacturing support.- Implemented communication tools and QA-compliant inventory transfer solutions with a Production site in Shanghai, China.- Provided technical support to the Supply Chain group during audit of Critical raw materials suppliers.- My team Introduced Quality Assurance compliant re-work procedures that lead in less than 3 months to more than $70,000 worth of raw material, reducing inventory scrap value by $135,000 and eliminating back-order for impacted products.- My group initiated, validated and implemented an automated dispensing procedure for a key component of the Bio-Plex kits. The automation of this process resulted in a cost reduction of 40% on labor. The early implementation of this procedure (2 months in advance on schedule) translated to total cost reduction of $25,000 for the launch of a NPD project.

Hercules, Ca, Us

Process Development, Transfers Optimization and Manufacturing support.Developed, transferred and optimized functional and/or analytical tools, experiments and assays to ensure continuous manufacturability of production processes (QC procedures, Continuous Improvement projects…) using statistical analysis approaches including, but not limited to, Specifications Analysis/Setting, Process Capability Indexes analysis (Graph Pad, JMP software).- Revised and/or developed several Quality Control assays (including, but not limited to, testing, validation and procedure revision and implementation):• Real-Time Nuclease contamination detection assay, reducing costs of the procedure by $80,000/year while improving the limit of detection by 3 fold. • Isothermal polymerase activity assay improvement, reducing cost of goods by 90%, hands-on time by 75%, experiment-to-experiment variation by 45% and increasing first pass rate to 99%. Trained and mentored Chemists on this project• Real-Time Isothermal Reverse-Transcriptase assay for activity quantification. This Real-Time dye-based assay increased unit definition accuracy by 60%, while reducing experiment-to experiment variation to 5%. Trained and mentored the whole QC group on this project.• Real-Time Isothermal DNA polymerase assay for activity quantification. Similar concept as for the Reverse-Transcriptase assay. Limited to troubleshooting assay for legal reasons.- Led troubleshooting studies of two customer complaint cases linked to potential quality issues. Provided clear Yes/No answer to upper management, ultimately saving respectively $850,000 and $600,000 worth of dispensed products. Developed procedures and new methods that were not available for future troubleshooting needs.

Hercules, Ca, Us

Protein Engineering, Enzymology and Formulation.Developed and transferred two new enzyme-based products, demonstrating solid records of achievement in team-oriented environment as well as strong capabilities to promote and facilitate communications between different teams.- Designed a new generation of Taq-based DNA polymerase for Fast Multiplex qPCR.- Designed two qPCR supermix products.- Initiated and managed a cross-laboratories scientific meetings and discussions to promote R&D teams’ interactions.- Actively participated in the Customers’ need awareness program, managing both onsite event and led an investigation team to Stanford University.

Berkeley, Ca, Us

Post-doctoral work: studied potential DNA topological barrier proteins (domainins) in E. coli.- Supervised one undergraduate student and mentored one graduate student.- Initiated and managed an external collaboration with UCSF to developed ChIP-Chip and genome wide analysis expertise in house.- Proposed and published the now accepted mechanistic model for DNA relaxation by Type-IA topoisomerases.

Thesis work: studied topoisomerase I from the hyperthermophile bacteria, Thermotoga maritima. - Supervised two Senior Chemists.- Designed and conducted studies for a better understanding of the topoisomerisation reaction catalyzed by Type-IA topoisomerases, using chimeric proteins.- Identified key enzymatic steps of the DNA topoisomerase I-mediated catalysis.- Initiated three active scientific collaborations leading to peer-reviewed publications.

Phd, Molecular Biology, Microbiology

Master, Microbiology