Timas (Shin-Yu) Kung Email & Phone Number

Manchester, Gb

- Develop and execute customized RNA-seq and single-cell RNA-seq analyses- Perform data analyses and visualizations

Taipei City, Taiwan

- Lead the design and execution of in-house experiments and analyses, generating crucial data and insights.- Presented meaningful findings to collaborators and other key stakeholders.- Managed external CROs and communication with academia collaborators.- Reviewed and shared relevant up-to-date literature and publications.- Drafted drug application-related documents for regulatory submission.- Oversaw technical and administrative functions for the company laboratory.

Taipei City, Taiwan

Stockholm, Sweden

Lisa Westerberg's group, Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, SwedenProject title: Understanding the role of actin regulation in dendritic cell adhesion and migrationSupervisor: Lisa WesterbergCo-supervisor: Mariana OliveiraDendritic cells patrol peripheral tissue and then migrate to secondary lymphoid organs to present encountered antigens. With mouse models of Wiskott-Aldrich syndrome and X-linked neutropenia, we investigated the effect of functional mutations in the Wiskott-Aldrich syndrome protein on dendritic cell adhesion and migration. Cell adhesion was measured in primary mouse cell cultures using confocal microscopy followed by ImageJ analysis with custom macros. Changes in dendritic cell migration in vivo were evaluated by a flow cytometry-based cell migration assay. Understanding these pivotal aspects of dendritic cell function may provide insight into immune regulation and aid immunotherapy design.

Stockholm, Sweden

Robert Harris' Group, Department of Clinical Neuroscience, Karolinska Institutet, SwedenProject title: Immunomodulation of microglia/macrophages as a potential therapy for neurological disordersSupervisor: Robert HarrisCo-supervisor: Keying ZhuDysregulated microglia activation triggers or exacerbates neuroinflammation, contributing to the development and progression of neurological disorders. Using primary mouse cell cultures and neuroinflammatory mouse models we identified compounds capable of mitigating microglia activation. The immunomodulatory effects were characterized in vitro with RT-PCR, ELISA, and cytometric bead arrays, while the in vivo effects were observed with animal behavior studies. These findings demonstrate the high plasticity of microglia and the potential of repurposing compounds for the management of microglia activation under neuroinflammatory conditions.

Hsinchu County/City, Taiwan

Wen-Ching Wang's group, Institute of Molecular & Cellular Biology, National Tsing Hua University, TaiwanProject title: Investigating the effect of KDM4B inhibitors on IL-8 production in gastric cancerSupervisor: Wen-Ching WangCo-supervisor: Meng-Chen WuOverexpression of IL-8 in gastric cancer is correlated with poor prognosis. The lysine demethylase KDM4B contributes to IL-8 production via epigenetic regulation. ELISA and RT-PCR revealed that KDM4B inhibitors do indeed reduce IL-8 expression in a gastric cancer cell line co-cultured with H. pylori, highlighting their potential as a treatment option for gastric and other cancers.

Hsinchu County/City, Taiwan

Hsinchu County/City, Taiwan

Kaohsiung City, Taiwan

Kaohsiung City, Taiwan

Master'S Degree, Biomedicine

Bachelor'S Degree, Medical Science, Electrical Engineering, Gpa 4.11

Activities and Societies: Captain of Departmental Football Team; Chair of the Economic and Social Council at 2015 Taiwan Model United.

Exchange Student, Biochemistry And Molecular Biology

High School Diploma

Activities and Societies: Founder and former President of Model United Nations Club