Uladzislau Hapko Email & Phone Number

Munich, BY, DE

Greater Munich Metropolitan Area

Saarbrücken, Saarland, Germany

Wrap-up postdoctoral stay

Darmstadt, Hesse, Germany

Saarbrücken Area, Germany

• Organic synthesis. Synthesized various ali- and heterocycles with diverse substitution patterns. Carried out various transition metal-catalyzed cationic cyclizations. Mastered various types of cross-coupling.
• Medicinal chemistry. Successfully implemented fragment-optimization and growing in the absence of structural data discovering a highly potent and ligand-efficient class of antitubercular compounds. - to be published.
• Organizational. Maintained and coordinated collaboration with 2 different partnering groups located in Germany. (Indirectly) interacted with a DMPK screening CRO abroad

Москва, Россия

• Organic synthesis. Mastered various types of organic transformations of carbohydrate-containing natural products. Synthesized and characterized more than 50 unique carbohydrate-containing building blocks relevant to.

Saint Petersburg, Russian Federation

• Organic synthesis of small molecule CDK-8 and EGFR inhibitors (featured in WO/2019/070167) Assembled 3 small-molecule libraries of project-specific com-pounds, each containing 10 molecules and sent them for biological.

Groningen, Netherlands

• Organic synthesis  Synthesized 25 relevant precursors for acylhydrazone-based protein-templated dynamic combinatorial chemistry.
• Docked and scored potential 15-LOX inhibitors using LeadIT and SeeSAR.
• In silico discovered one of the most potent 15-LOX inhibitors (featured in 10.1016/j.ejmech.2019.04.021)

Doctor Of Philosophy - Phd, Medicinal And Pharmaceutical Chemistry

Master Of Science - Ms, Organic Chemistry, 4.8/5

Activities and Societies: Alpine Club (Climbing & Mountaineering)

High School, Chemistry