Assistant Professor Of Chemistry (Research)
Research with Prof. David E. Cane.“Mechanistic characterization of microbial terpene synthases and biosynthetic pathways.”• Synthesized and evaluated 2-methylneryl diphosphate as a substrate analogue for 2-methylisoborneol synthase.• Synthesized chirally pure (3R)-nerolidyl diphosphate for its evaluation as a substrate for amorphadiene synthase.• Characterized the enzymatic product distributions of multiple terpene synthases and mutants for protein structure-activity… Show more Research with Prof. David E. Cane.“Mechanistic characterization of microbial terpene synthases and biosynthetic pathways.”• Synthesized and evaluated 2-methylneryl diphosphate as a substrate analogue for 2-methylisoborneol synthase.• Synthesized chirally pure (3R)-nerolidyl diphosphate for its evaluation as a substrate for amorphadiene synthase.• Characterized the enzymatic product distributions of multiple terpene synthases and mutants for protein structure-activity relationships.• Synthesized terpene products for use as standards in mass spectrometry.• Evaluated enzyme activities using mass spectrometry and enzyme kinetics. Show less