Widler Casy, Ph.D. Email & Phone Number

Boston, MA, US

Gainesville, Florida, United States

• Develop and optimize bioanalytical assays for protein detection, vector DNA quantification, and vector RNA transcript quantification.
• Lead the establishment and implementation of a comprehensive infrastructure for tissue processing, ensuring high-quality sample preparation and analysis.
• Process hundreds of animal tissues, including mouse and non-human primate tissues, for vector DNA quantification, vector RNA quantification, and protein detection.
• Collaborate with contract research organizations (CROs) to design and oversee animal studies, ensuring timely and accurate data generation.
• Assist in establishing strategic partnerships with academic principal investigators (PIs), fostering collaborations and leveraging their expertise.
• Generate intellectual property through innovative technology development, contributing to the company's portfolio and assets.

Gainesville, Florida, United States

Gene Therapy - R&DOur team team is developing gene therapy drugs to treat people who suffer from genetic diseases. Visit us at https://www.aavantibio.com/ to learn more about what we do, how we do it, and of course why we do what we do.

Dallas, Texas

• Gene Therapy
• Our laboratory uses adeno-associated viruses (AAV) as gene delivery vectors to target a wide range of rare genetic diseases which include Giant Axonal Neuropathy (GAN), Batten disease, Rett syndrome, Pitt-Hopkins.
• My primary research focus is to develop novel AAV vectors that can cross the blood brain barrier and target different areas of the brain with high specificity and low toxicity to peripheral organs
• Approaches that I am using to engineer these novel AAV vectors include:o Rational design o capsid shuffling
• Facets of my projects also involve clinical trial phases

• Investigated the mechanism of protein synthesis in bacteria using cutting-edge single molecule biophysics methods and technology
• Designed and executed two major projects to completion
• Collaborated with internal and external research groups
• Received grant writing training and wrote several research proposals
• Served as consultant in grant writing with collaborators
• Generated data for grants and fellowship applications

Saint Charles, Missouri

• Performed independent study of soil strata at The Historic Daniel Boone Home in St Charles Missouri
• Carried out plant pathology based assay
• Contributed to the design and construction of a compost pile system to convert waste from the greenhouse into natural fertilizers
• Coordinated undergraduate’s general biology and advance plant biology laboratory courses by providing various plant species upon request and helping with students’ hands experiences
• Recorded and maintained an up-to-date inventory of greenhouse and laboratory supplies
• Trained and supervised new student-workers

Lansing, Michigan Area

• Participated in the 2012 Summer Research Opportunity Program (SROP) at Michigan State University in the Pharmacology and Toxicology Department
• Investigated the role of enterochromaffin cells in visceral hypersensitivity and in gastrointestinal track diseases such as ulcerative colitis and irritable bowel syndrome
• Operated a microtome (Cryostat) to generate thin cross section of rats’ intestines
• Performed immunohistochemistry using thin cross-section of intestinal tissues derived from rats
• Received training on data analysis (ANOVA, Chi-square test, Student's t-test …) using various statistical software which include R, SAS, and SPSS
• Attended numerous workshops tailored for scientific writing, science communication/public speaking, and leadership development

Doctor Of Philosophy - Phd, Biochemistry

Bachelor Of Science - Bs, Chemistry With An Emphasis In Biochemistry, Cum Laude

Activities and Societies: Alpha Chi Honor Society