Will Scott Email & Phone Number

Watertown, Massachusetts, United States

• Biology lead for 3 development and clinical stage programs • Manage in vivo studies at CROs• Design and execute various experiments to answer biological questions posed by the team • Manage the cell banking workflow • Culture various mammalian cell lines (suspension and adherent) simultaneously • Generate slide decks to communicate research findings to the cross-functional team, allowing for quick, concise go/no-go decisions

Greater Boston

• Developed and validated 10+ custom cell-based assays and ELISAs to characterize and screen novel immuno-oncology therapeutics, leading to go/no-go decisions • Optimized enzymatic cleavage reactions to enhance efficiency, mitigate downstream effects, and streamline high-throughput assays• Developed and implemented assays for clinical stage molecules; worked with key stakeholders to ensure the development team was aligned with techniques, progress, and results. Documented findings in a report for regulatory filing• Generated data on molecules across the platform aligned with the programs’ target candidate profile (TCP) to enable the selection of development candidates (DCs) and IND filings • Cultured and maintained multiple cell lines (adherent and suspension) simultaneously• Cryopreserved and banked cells for the department following established LIMS practices • Performed routine assays to QC 1000+ molecules for release for downstream characterization assays and to funnel candidates for DC nomination• Maintained detailed experimental information and data analyses in ELN entries • Generated and presented figures and slide decks to communicate results and proposals for interdepartmental project team meetings, allowing for quick, clear decisions • Wrote and transferred SOPs to internal departments and CROs, allowing for seamless and timely transition of assays and key data generation• Served as the Cell Pharmacology representative for three cross-functional discovery projects. Collaborated interdepartmentally on complex experiments and data packages to inform platform questions and project teams• Reviewed literature and remained informed on the latest advances in the competitive landscape and was an active member of the Xilio Journal Club• Collaborated with the CMC, Non-clinical Development, Toxicology, and Clinical teams• Served as a member of the laboratory safety committee to ensure compliance with local regulations

• Editor and Reviewer in the Neuroscience and Neurology Division• Provided feedback and grammatical edits of 165+ pre-publication scientific manuscripts and documents for international clientele, resulting in >90% positive client feedback • Navigated everchanging deadlines to maintain a 100% deadline conformance

Toronto, Canada Area

• Spearheaded a team of four researchers to investigate the role of a chromatin remodeler in cancer initiation and suppression, resulting in a first-author publication • Generated and characterized 8+ isogenic cell lines to perform BioID, identifying 500+ protein associations for follow-up studies • Cloned and expressed numerous expression plasmids to purify recombinant proteins for downstream protein interaction assays, including immunoprecipitations and Western blotting• Independently designed, optimized, and implemented protocols for techniques, including immunofluorescence, FISH, and CRISPR • Developed projects and authored proposals to secure four scholarships totaling $100,000+ • Mentored ten trainees, two technicians, and one postdoc to execute research effectively

Auburn, Alabama Area

• Assisted in the study of copper transport in the yeast Saccharomyces cerevisiae

Auburn, Alabama Area

• Authored a research proposal to obtain a competitive research fellowship• Developed and headed a project exploring the effects of heat stress on gene expression in cotton, resulting in a study pipeline used by future students, and cumulating in an honors thesis

Auburn, Alabama Area

• Assisted with the introductory Honors Freshman Exploration course by delivering lectures and grading assignments for a class of 25 students• Introduced students to the Auburn University Honors College curriculum and university services to guide their undergraduate experience

Doctor Of Philosophy - Phd, Molecular Genetics, 4.0/4.0

Thesis: The ATRX Chromatin Remodelling/Helicase Protein Maintains Telomere Integrity Through its Protein Associations

Honors Bachelor’S Degree, Microbial, Cellular, & Molecular Biology And French, 3.7/4.0

Activities and Societies: French Club (Aug 2012-May 2016) University Honors Scholar, Magna cum laude Honors thesis: A Transcriptomic.