William Mcghee Email and Phone Number

CMC process development for startup biotech including drug product and drug substance activities. Nanoparticle delivery, API development, CDMO management

Led a team of three (3) to five (5) technical professionals within R&D emphasizing new formulations• Process development for phosphoramidites, 8-Methoxysalen, and isolation / purification of Hemin• Development of PLGA - Poly (lactic-co-glycolic acid) - micro-particle formulations• Developed liposomal formulations of pharmaceutical candidate molecules for the oncology, pain and autoimmune arenas (including peptides and small molecules)• Department Nuclear Magnetic Resonance (NMR) specialist• Due diligence and new opportunity identification• Safety Committee Member trained in HAZMAT, CPR and First AidSenior Research Specialist (2008 to 2014)Lead Scientist for Nanoparticle Group supervising three (3) scientists• Core Team Member for Liposomal Docetaxel and Liposomal Oxaliplatino pro-drug development, IND preparation (drug product section), and IP generationo material generation and manufacturing site selectiono technical transfer to contract research and/or manufacturing organizations• Generation of multiple liposomal materials as potential next generation products (gemcitabine, cisplatin and carboplatin as examples)• Key collaborative role and idea generator for use of Vascular Disruption Agent’s (VDA’s) as tumor modifiers to enhance nanoparticle effectiveness• Created and led the “Potent Suite” after designing, start-up and training staff on the proper safety procedures and utilization of the lab and the equipment• Completed Six Sigma course work and integrated concepts into Nanoparticle Group activities• Recipient of two (2) Innovator Awards

As chemistry director supervised 4-6 employees, including synthetic chemists, analytical chemists and formulation scientists. Served as main contact for contract work for production of GMP APIs and for product formulations. Pharmaceutical products developed as nano-emulsions using micro-fluidization techniques. API's generated and coupling chemistry developed for nano-emulsion incorporation.

Scientist for deformulation and product characterization.

As Science Fellow supervised 2-4 employees, developed patented processes, developed zeolite catalysts, homogeneous catalysts for asymmetric synthesis and for coupling chemistry and patented several aspects of carbon dioxide chemistry (Green Chemistry).