Kalocyte, Inc.

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KaloCyte, Inc., a preclinical biotech that has developed an artificial RBC substitute for use as a lifeline when blood is not available. We are located at the University of Maryland, Baltimore (UMB) as an Affiliate of the UM BioPark, and were selected as a BLUE KNIGHT™ Company. KaloCyte offices and labs are sited within the UM School of Medicine’s Center for Blood Oxygen Transport and Hemostasis (CBOTH) directed by Allan Doctor, MD (KaloCyte Co-Founder and CSO). KaloCyte was founded in 2016 by a distinguished team of Washington University in St. Louis researchers in physiology, bioengineering, and trauma care, with support from the BioGenerator Fundamentals program. KaloCyte has demonstrated preclinical safety and efficacy for ErythroMer, a shelf-stable, bio-inspired artificial red blood cell envisioned for use when stored red blood cells are unavailable, undesirable or in short supply. KaloCyte is supported by $17M in federal awards and $5M investor funding. ErythroMer is a first-in-class, bio-inspired nanoparticle-encapsulated human hemoglobin, which mimics the vital oxygen-carrying functionality of RBCs and can be freeze-dried for long-term storage. Erythromer’s synthetic outer membrane, small size and surface area allow for physiologically realistic gas exchange. The synthetic polymer shell is “immune-silent”, inert and carries no blood antigens, eliminating the need to type and cross-match as with stored blood. ErythroMer can be freeze-dried or “lyophilized”, for a much longer shelf life than stored blood. It is covered by issued U.S. patents that specify composition of matter, method of preparation, and use as an oxygen carrier.
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Baltimore’s KaloCyte Partners on $46M DARPA Program to Develop Synthetic Blood Product - BioBuzz

Baltimore’s KaloCyte Partners on $46M DARPA Program to Develop Synthetic Blood Product BioBuzz

Scorpius Holdings Partners with KaloCyte to Enhance Manufacturing of Innovative Blood Substitute ErythroMer - Nasdaq

Scorpius Holdings Partners with KaloCyte to Enhance Manufacturing of Innovative Blood Substitute ErythroMer Nasdaq

Scorpius Holdings Announces Collaboration with KaloCyte to Advance Manufacturing for ErythroMer™ - GlobeNewswire

Scorpius Holdings Announces Collaboration with KaloCyte to Advance Manufacturing for ErythroMer™ GlobeNewswire

Scorpius Partners with KaloCyte on Revolutionary Artificial Blood Cell Manufacturing - Stock Titan

Scorpius Partners with KaloCyte on Revolutionary Artificial Blood Cell Manufacturing Stock Titan

Synthetic, shelf-stable blood developed by Maryland scientist could save lives in emergencies - CBS News

Synthetic, shelf-stable blood developed by Maryland scientist could save lives in emergencies CBS News

Founders Week 2022: David J. Ramsay Entrepreneur of the Year Allan Doctor, MD - The University of Maryland, Baltimore

Founders Week 2022: David J. Ramsay Entrepreneur of the Year Allan Doctor, MD The University of Maryland, Baltimore

Redesigning Blood for the Battlefield and Beyond - SynBioBeta

Redesigning Blood for the Battlefield and Beyond SynBioBeta

Penn State scientist plays key role in $46M artificial blood research program - Penn State University

Penn State scientist plays key role in $46M artificial blood research program Penn State University

A strategic relocation to Baltimore supports one biomedical company’s growth - Technical.ly

A strategic relocation to Baltimore supports one biomedical company’s growth Technical.ly

Pitt and UPMC Play Key Role in Ambitious Federal Initiative to Create Artificial Dried Whole Blood - UPMC

Pitt and UPMC Play Key Role in Ambitious Federal Initiative to Create Artificial Dried Whole Blood UPMC

Q&A: Synthetic blood startup's new CEO hopes to bring product to hospitals, battlefields and eventually Mars - The Business Journals

Q&A: Synthetic blood startup's new CEO hopes to bring product to hospitals, battlefields and eventually Mars The Business Journals

Inside US military's $46 million bet to develop ultimate blood substitute - Times of India

Inside US military's $46 million bet to develop ultimate blood substitute Times of India

Entrepreneur of Year Discusses Development of Artificial Blood - The University of Maryland, Baltimore

Entrepreneur of Year Discusses Development of Artificial Blood The University of Maryland, Baltimore

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