Jinjin Wu Email & Phone Number

Redmond, Washington, United States

Durham, North Carolina, United States

- Thesis project 1: Investigated the role of 10q23 lesions on prostate tumorigenesis through a multidisciplinary approach including patient genomic data analyses, generation of CRISPR/Cas9 engineered mouse models, transcriptional profiling and unbiased in vivo CRISPR screens.- Thesis project 2: Investigated the oncogenic role of fatty acid-CoA ligase ACSL4 in advanced prostate cancer through high-throughput transcriptional and lipidomic profiling validated by functional analyses and… Show more - Thesis project 1: Investigated the role of 10q23 lesions on prostate tumorigenesis through a multidisciplinary approach including patient genomic data analyses, generation of CRISPR/Cas9 engineered mouse models, transcriptional profiling and unbiased in vivo CRISPR screens.- Thesis project 2: Investigated the oncogenic role of fatty acid-CoA ligase ACSL4 in advanced prostate cancer through high-throughput transcriptional and lipidomic profiling validated by functional analyses and developed novel pharmacological ACSL4 inhibitors through in silico and in vitro screening that effectively inhibited prostate cancer tumor growth. Show less

Birmingham, Alabama, United States

- Supported NIH R01 grant applications by collecting preliminary data, creating figures, and writing up proposals for submission.- Designed and conducted in vitro and in vivo experiments to explore the function of important transcriptional factors during bone development and homeostasis.- Characterized the functions of CBX3, an epigenetic factor involved in osteoclasts and immune cells regulation through genome-wide analysis, in vitro functions determination and animal model studies.

New York, United States

- Collaborated on identification of epigenetic biomarkers to study the association between smoking status and the incidence of hepatocellular carcinoma, performed pyro-sequencing experiments, conducted data cleaning and statistical analysis from a prospective cohort.- Provided statistical analysis for a genome-wide association study using NHANES database to explore the role of BMI-related genes in hepatocellular carcinoma caused by HBV infection.

Beijing City, China

- Led the project to study the impact of prenatal exposure to nanosilver particles on short-term memory of rats through immunohistochemical analyses, pathological analyses of hippocampal microsections, HPLC analyses and RT-PCR assay.- Supported application of experimental approaches to the toxicological assessment of an environmental agent panel to explore statistics-based evidence to identify novel neurotoxicants.

Los Angeles, Ca

- Optimized protocols for quantitative analysis of germline cell apoptosis in C. elegans, applied experimental method to perform a large-scale screening under wide-field microscope.- Analyzed data from screening result, calculated apoptotic index and assessed potential reproductive toxicity of 50 flame retardant agents.

Doctor Of Philosophy - Phd, Pathology/Experimental Pathology

Activities and Societies: OBGE Peer mentor year 2022-2023 - Highlighted Coursework: Systemic Histology, General Pathology, Molecular.

Mph, Environmental Health Sciences, 3.88/4.00

Activities and Societies: Member, Chinese Student and Scholar Association at Columbia University Medical Center, Oct 2015-May 2017..

Bs, Environmental Science

Activities and Societies: Co-Organizer/Volunteer teacher in Haidian Migrant Elementary School, Sep 2012 - Jan 2013 - Academic Awards.