• Produced and benchmarked matched and unmatched somatic variant calling results using 5 variant callers—MuTect2, MuSE, Strelka, VarScan, and ISOWN.• Developed an unmatched somatic single nucleotide variant calling pipeline.• Processed 93 human colorectal cancer samples and the pipeline identified variants with high precision and led to accurate mutational signature extraction with SigProfilerPro.• Presented at the West Coast Biological Sciences Undergraduate Research… Show more • Produced and benchmarked matched and unmatched somatic variant calling results using 5 variant callers—MuTect2, MuSE, Strelka, VarScan, and ISOWN.• Developed an unmatched somatic single nucleotide variant calling pipeline.• Processed 93 human colorectal cancer samples and the pipeline identified variants with high precision and led to accurate mutational signature extraction with SigProfilerPro.• Presented at the West Coast Biological Sciences Undergraduate Research Conference.• Engaged in discussion with 10+ undergraduates and faculties on the impacts and future directions of the project.• Communicated the science with attendants at The National Conference on Undergraduate Research and UC San Diego Undergraduate Research Conference.• Completed a senior honors thesis in the School of Biological Sciences and graduated with distinction.• Presented my poster at the School of Biological Sciences Annual Student Research Showcase. Show less

• Modeled the 3D structure of the human male X chromosome across 9 cancer cell lines from tissues including kidney, lung, and colon using Chrom3D and ChimeraX.• Developed Python code on Jupyter Notebook and Snakemake to streamline analysis, validation, and visualization of 3D spatial data against 1D data including expression level and A/B compartments.• Debugged TADsplimer on the HPC cluster system by testing each step of the tool with validated ENCODE data.• Collaborated with three… Show more • Modeled the 3D structure of the human male X chromosome across 9 cancer cell lines from tissues including kidney, lung, and colon using Chrom3D and ChimeraX.• Developed Python code on Jupyter Notebook and Snakemake to streamline analysis, validation, and visualization of 3D spatial data against 1D data including expression level and A/B compartments.• Debugged TADsplimer on the HPC cluster system by testing each step of the tool with validated ENCODE data.• Collaborated with three lab members to learn and employ various statistical analysis and HiC-related tools such as Seaborn, Juicebox, and dcHiC.• Presented in the 2021 Online Undergraduate Research Symposium to undergraduates and professors.• Communicated results and progress through UC San Diego Faculty Mentor Program's final write-up report. Show less

• Medicines Innovation Hub Talent Development Academy's internship program.• Assigned to the Biological Development and Research Department at Lilly Biotechnology Center.• Created an up-to-date, comprehensive, well-annotated, and queryable database of thousands of entries to enable novel explorations that reduce cost, boost productivity, and enhance quality.• Communicated the science and its business impact to the company through a 30-minute presentation and 20+ pages of manuscript… Show more • Medicines Innovation Hub Talent Development Academy's internship program.• Assigned to the Biological Development and Research Department at Lilly Biotechnology Center.• Created an up-to-date, comprehensive, well-annotated, and queryable database of thousands of entries to enable novel explorations that reduce cost, boost productivity, and enhance quality.• Communicated the science and its business impact to the company through a 30-minute presentation and 20+ pages of manuscript in Nature research article format. Show less

• Investigated the role of protein deamidation in the host’s response to Kaposi's sarcoma-associated herpesvirus.• Assisted under a graduate student in the lab for 6 hrs/ day, 6 days/ week.• Generated helpful data, especially through DNA electrophoresis.