ACRNS Analytical Technologies Pvt Ltd

ACRNS analytical technologies provides services in the area of analytical consultation, laboratory setup, training of analysts in instrumentation & data interpretation, & development of workflows for regulatory submission. Workflows and services: 1. Exploration of suitable analytical strategy customized for molecule type and nature of sample. 2. Establishing a multiple attribute method for evaluation of change in process. 3. Introduction of customized workflows for testing of in-process samples using hyphenated techniques. 4. Introduction of mass-spectrometry based methods in quality control laboratories for routine in-process testing, investigative studies and process optimization, scale-up studies. 5. Implementing advanced applications of mass spectrometry for higher order structure comparison between innovator & biosimilar as well as between biosimilars before and after process change. 6. Support to regulatory submissions and handling of queries from regulators in case of high-end characterization involving rare expertise or difficult to investigate a structural modification. 7. Support to physico-chemical characterization for biosimilarity demonstration through use of techniques such as LC-MS/MS, ICP-MS, FTIR, & other biophysical tools. 8. Support to data processing & interpretation. ACRNS analytical technology is an official distributor of Innovative Technologies such as: Protein metrics software: PMI is a state-of-art tool for interpretation of mass spectrometry data for proteins & peptides. With the addition of Oligonucleotide Module, PMI now enables accurate analysis of oligonucleotides, offering detailed insights for both proteomics & oligonucleotide research. LabSmith Products: LabSmith’s customizable microfluidic and automation solutions empower engineers and researchers to design and implement their experiments. BaySpec Portable MS: These compact systems deliver reliable, high-quality results, making them ideal for both fieldwork & laboratory.