Biological barriers protect our body from harmful effects. They also block the penetration of therapeutics and make pharmacological treatments of different organs, like the brain difficult. In addition, they may be damaged in illnesses, like diabetes, Alzheimer’s or Parkinson’s diseases, or acute pancreatitis.
Our goal is
1. to develop novel devices and models for the investigation of biological barriers
2. to enhance drug penetration across biological barriers by new techniques
3. to protect barriers in disease conditions
We use human cell based culture models of the blood-brain, the intestinal, the lung, the bronchial, the nasal and the cornea barriers. In addition to static culture models we also use organ-on-chip devices with flow to mimic the physiological conditions. Currently we test peptides to open or cross barriers and nanoparticles targeted for the transporters of the blood-brain barrier. Our group is expert in cellular toxicity assays, barrier function and drug penetration measurements, preparation, characterization and testing vesicular nanoparticles.
Company Details
- Employees
- 12
- Founded
- -
- Address
- Temesvári Körút 62, Rm 227,hungary
- Industry
- Research Services
- NAICS
-
Scientific Research and Development ServicesResearch and Development in the Physical, Engineering, and Life SciencesResearch and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)
- Keywords
- Scientific research, Drug delivery, Biological barriers, Drug testing, Nanoparticles, Culture models, Organ-on-chip, Blood-brain barrier, Lung barrier, Gut barrier, Cell viability tests, Barrier opening with peptides, Nasal barrier, Cornea barrier, Epithelial cells, Endothelial cells, Toxicity assays, Impedance measurements.
- HQ
- Szeged, Hungary
Biological Barriers Research Group Questions
Biological Barriers Research Group's website is http://www.brc.hu/hu/kutatas/biofizikai-intezet/molekularis-neurobiologia-kutatoegyseg/biologiai-barrierek-kutatocsoport
Biological Barriers Research Group's LinkedIn profile is https://hu.linkedin.com/company/bbrg
Biological Barriers Research Group has
12 employees.
View email and phone details for 12
employees at Biological Barriers Research Group.
Biological Barriers Research Group's industry is
Research Services
Biological Barriers Research Group's top competitors are
Gutvibrations,
Myleukaemia Project,
Flamin-Go Project,
Myochip,
Get-In Dn Msca,
Organ-On-Chip,
Mimiclab,
Nanomatronix,
Scientisst,
International Brain Barriers Society (Ibbs).
Biological Barriers Research Group's categories are Research Services
Biological Barriers Research Group's founding year is 2001
