C3G company information, Employees & Contact Information

What to know about C3G treatments, from lifestyle adjustments to medications and dialysis Mayo Clinic Press

Clinical Trials for IgAN and C3G: Are They Right for You? Cleveland Clinic Health Essentials

C3G improves lipid droplet accumulation in the proximal tubules of high-fat diet-induced ORG mice ScienceDirect.com

Effective long-term treatment with moss-produced factor H by overcoming the antibody response in a mouse model of C3G Frontiers

What To Eat (and Avoid) When Living With IgA Nephropathy or C3G Cleveland Clinic Health Essentials

Managing Symptoms and Slowing the Progression of IgA Nephropathy and C3G Cleveland Clinic Health Essentials

Novartis receives third FDA approval for oral Fabhalta® (iptacopan) – the first and only treatment approved in C3 glomerulopathy (C3G) Novartis

Expression of a novel brain specific isoform of C3G is regulated during development Nature

Diagnosed With C3G? Here’s Why You Should Consider Genetic Testing Cleveland Clinic Health Essentials

Quantifying association of early proteinuria and estimated glomerular filtration rate changes with long-term kidney failure in C3 glomerulopathy and immune-complex membranoproliferative glomerulonephritis using the United Kingdom RaDaR Registry ScienceDirect.com

New functions of C3G in platelet biology: Contribution to ischemia-induced angiogenesis, tumor metastasis and TPO clearance Frontiers

Diagnosed With IgAN or C3G? Here’s What To Expect Cleveland Clinic Health Essentials

Comparative Analysis of Proteinuria and Longitudinal Outcomes in Immune Complex Membranoproliferative Glomerulonephritis and C3 Glomerulopathy ScienceDirect.com

C3 glomerulopathy: a kidney disease mediated by alternative pathway deregulation Frontiers

Efficacy and Safety of Pegcetacoplan in Kidney Transplant Recipients With Recurrent Complement 3 Glomerulopathy or Primary Immune Complex Membranoproliferative Glomerulonephritis ScienceDirect.com

CFH and CFHR Copy Number Variations in C3 Glomerulopathy and Immune Complex-Mediated Membranoproliferative Glomerulonephritis Frontiers

Outcome of Patients Transplanted for C3 Glomerulopathy and Primary Immune Complex-Mediated Membranoproliferative Glomerulonephritis ScienceDirect.com

Living With IgA Nephropathy and C3G Kidney Diseases Cleveland Clinic Health Essentials

Alternative Complement Pathway Inhibition With Iptacopan for the Treatment of C3 Glomerulopathy-Study Design of the APPEAR-C3G Trial ScienceDirect.com

Iptacopan Reduces Proteinuria and Stabilizes Kidney Function in C3 Glomerulopathy ScienceDirect.com

Kidney Transplantation in Children and Adolescents With C3 Glomerulopathy or Immune Complex Membranoproliferative Glomerulonephritis: An International Survey of Current Practice Wiley Online Library

Complement Factor I Variants in Complement-Mediated Renal Diseases Frontiers

Crk proteins activate the Rap1 guanine nucleotide exchange factor C3G by segregated adaptor-dependent and -independent mechanisms Cell Communication and Signaling

C3G, through its GEF activity, induces megakaryocytic differentiation and proplatelet formation Cell Communication and Signaling

C3G contributes to platelet activation and aggregation by regulating major signaling pathways Nature

Functional Characterization of Rare Genetic Variants in the N-Terminus of Complement Factor H in aHUS, C3G, and AMD Frontiers

Childhood onset C3 glomerulopathy: recurrence after kidney transplantation—a case series Frontiers

Cyanidin-3-O-glucoside protects human gastric epithelial cells against Helicobacter pylori lipopolysaccharide-induced disorders by modulating TLR-mediated NF-κB pathway ScienceDirect.com

Cyanidin-3-O-Glucoside Protects against 1,3-Dichloro-2-Propanol-Induced Reduction of Progesterone by Up-regulation of Steroidogenic Enzymes and cAMP Level in Leydig Cells Frontiers

Cyanidin-3-galactoside from Aronia melanocarpa ameliorates PM10 induced pulmonary injury by modulating M1/M2 macrophage polarization and NRF2/Sirt1 MAPK signaling ScienceDirect.com

Cyanidin-3-glucoside attenuates silica-induced pulmonary inflammatory responses by modulating T cell immune responses and STAT1/STAT3 signaling ScienceDirect.com

The anthocyanin cyanidin-3-O-β-glucoside modulates murine glutathione homeostasis in a manner dependent on genetic background ScienceDirect.com

Use of Bortezomib in the Treatment of C3 Glomerulonephritis Refractory to Eculizumab and Rituximab ScienceDirect.com

Factor H Autoantibodies and Complement-Mediated Diseases Frontiers

Cyanidin-3-glucoside protects liver from oxidative damage through AMPK/Nrf2 mediated signaling pathway in vivo and in vitro ScienceDirect.com

Cyanidin-3-O-glucoside extracted from the Chinese bayberry (Myrica rubra Sieb. et Zucc.) alleviates antibiotic-associated diarrhea by regulating gut microbiota and down-regulating inflammatory factors in NF-κB pathway Frontiers

C3-Glomerulopathy Autoantibodies Mediate Distinct Effects on Complement C3- and C5-Convertases Frontiers

The anticancer effects of cyanidin 3-O-glucoside combined with 5-fluorouracil on lung large-cell carcinoma in nude mice ScienceDirect.com

Novel Rap1 dominant-negative mutants interfere selectively with C3G and Epac Nature