Most of the current tumor-targeted antibodies only serve a subset of patients and a subset of cancers. Many of them also unintentionally target healthy tissues, causing severe side effects.
We aim to become the leading provider of truly tumor-specific monoclonal antibody (mAb) based therapies for all patients, for all cancer types, without targeting healthy cells.
Sugars (glycans) play a crucial role in modifying many essential proteins in our bodies, including those found on the surfaces of cancer cells. In most cancers, these sugar structures are shortened compared to healthy cells, offering a unique opportunity to differentiate between cancerous and normal cells.
Combotope Therapeutics has developed a proprietary mAb discovery platform designed to target cancer cells without impacting healthy cells. Our platform, known as integrated Design Antibody Libraries (iDEAL), combines glycan and peptide-focused scFv technology, providing antibodies that specifically target the tumor form of a particular protein on cancer cells while leaving healthy cells expressing the same, but correctly glycosylated protein, untouched. Our scFv sequences are of high affinity, making them suitable for easy integration into numerous therapeutic modalities for effective cancer treatment.
Our business model involves identifying, developing, and licensing proprietary scFv sequences that specifically target cancer proteins with aberrant O-glycosylation.
Through strategic partnerships, we will accelerate the development and commercialization of pioneering scFv-based off-the-shelf and personalized anti-cancer therapies.
Company Details
- Employees
- 3
- Founded
- -
- Address
- Diplomvej 381, Lundtofte,capital Region Of Denmark 2800,denmark
- Industry
- Pharmaceutical Manufacturing
- NAICS
-
Pharmaceutical and Medicine ManufacturingMedicinal and Botanical ManufacturingPharmaceutical Preparation ManufacturingIn-Vitro Diagnostic Substance ManufacturingBiological Product (except Diagnostic) Manufacturing
- Keywords
- Therapeutic antibody development, Oncology, mAb, Aberrant glycosylation, scFv, cancer, ADC, Bispecific, CAR-T cell, BiTE.
- HQ
- Lundtofte, Capital Region of Denmark
Combotope Therapeutics Aps Questions
Combotope Therapeutics Aps's website is http://www.combotopetherapeutics.com
Combotope Therapeutics Aps's LinkedIn profile is https://dk.linkedin.com/company/combotope-therapeutics-aps
Combotope Therapeutics Aps has
3 employees.
View email and phone details for 3
employees at Combotope Therapeutics Aps.
Combotope Therapeutics Aps's industry is
Pharmaceutical Manufacturing
Combotope Therapeutics Aps's top competitors are
Agrobiomics,
2n Pharma,
Adcendo,
Venomab,
Lead Biologics,
Venomaid Diagnostics,
Pharmalex,
Monta Biosciences,
Nanovi A/s,
Antag Therapeutics.
Combotope Therapeutics Aps's categories are Pharmaceutical Manufacturing
Combotope Therapeutics Aps's founding year is 2023
