ExpoSignalz

A European research project studying the effects of environmental pollutants on brain health and their role in neurodegenerative diseases launched in January 2025. ExpoSignalz has been awarded funding from Horizon Europe, the European Union’s research and innovation programme. Led by the National Institute of Health and Medical Research (INSERM) in France, the project will use interdisciplinary approaches, combining experimental and epidemiological studies, to address this pressing global health challenge. Over five years, the ExpoSignalz project aims to uncover how specific chemical pollutants, such as persistent organic pollutants, electronic waste, and pharmaceutical residues, affect brain ageing and contribute to dementia, a leading cause of death worldwide. Researchers will investigate these impacts across life stages, with a focus on understanding their mechanisms and developing strategies for early diagnosis and prevention of Alzheimer’s disease, which accounts for 70% of dementia cases. ExpoSignalz has received funding from the European Union’s Horizon Europe Research and Innovation programme under grant agreement 101156353.