Iecure, Inc.

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iECURE is a clinical-stage gene editing company focused on delivering cures and transforming the lives of patients with devastating liver disorders, utilizing new advancements in genetic medicine. We believe our in vivo gene insertion approach has the potential to restore the function of a dysfunctional gene, regardless of mutation, by inserting a functional copy of that gene to provide durable gene expression and long-term, potentially curative, therapeutic benefit. The company is advancing a pipeline of genetic medicines, led by ECUR-506, an investigational gene editing therapy in clinical development for the treatment of neonatal onset ornithine transcarbamylase (OTC) deficiency. iECURE is proud to be recognized as one of the Philadelphia Business Journal’s “Best Places to Work” for the second year in a row and was named to Fierce Biotech’s “Fierce 15” in 2024. We are headquartered in Blue Bell, PA.
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iECURE to Present Initial OTC-HOPE Clinical Trial Data of ECUR-506 in Ornithine Transcarbamylase Deficiency at 6 - Business Wire

iECURE to Present Initial OTC-HOPE Clinical Trial Data of ECUR-506 in Ornithine Transcarbamylase Deficiency at 6 Business Wire

Clinical trial: Long-term Follow-up Study of Participants in Any iECURE Protocol Using an Investigational Product, (NCT06805695) - CRISPR Medicine News

Clinical trial: Long-term Follow-up Study of Participants in Any iECURE Protocol Using an Investigational Product, (NCT06805695) CRISPR Medicine News

iECURE to Present OTC-HOPE Clinical Trial Data of ECUR-506 in Ornithine Transcarbamylase Deficiency at the European Society of Gene & Cell Therapy Annual Congress and the American Society of Human Genetics Annual Meeting - Business Wire

iECURE to Present OTC-HOPE Clinical Trial Data of ECUR-506 in Ornithine Transcarbamylase Deficiency at the European Society of Gene & Cell Therapy Annual Congress and the American Society of Human Genetics Annual Meeting Business Wire

iECURE Reports Complete Clinical Response in First Infant Dosed with its In Vivo Gene Editing Candidate ECUR-506 in an Ongoing Phase 1/2 Clinical Trial in Ornithine Transcarbamylase (OTC) Deficiency - Business Wire

iECURE Reports Complete Clinical Response in First Infant Dosed with its In Vivo Gene Editing Candidate ECUR-506 in an Ongoing Phase 1/2 Clinical Trial in Ornithine Transcarbamylase (OTC) Deficiency Business Wire

iECURE emerges with $50M to search for 'holy grail' and 'untapped frontier' of gene editing - Fierce Biotech

iECURE emerges with $50M to search for 'holy grail' and 'untapped frontier' of gene editing Fierce Biotech

iECURE gene therapy data suggests partial restoration of functional OTC - Clinical Trials Arena

iECURE gene therapy data suggests partial restoration of functional OTC Clinical Trials Arena

FDA grants fast track status for iECURE’s OTC deficiency therapy - Pharmaceutical Technology

FDA grants fast track status for iECURE’s OTC deficiency therapy Pharmaceutical Technology

iECURE Announces Presentation of Full Data for the First Infant Dosed with ECUR-506 in OTC-HOPE Phase 1/2 Clinical Trial at the 2025 ACMG Annual Clinical Genetics Meeting - BioSpace

iECURE Announces Presentation of Full Data for the First Infant Dosed with ECUR-506 in OTC-HOPE Phase 1/2 Clinical Trial at the 2025 ACMG Annual Clinical Genetics Meeting BioSpace

Gene editing startup iECURE returns to investors for fresh funding - BioPharma Dive

Gene editing startup iECURE returns to investors for fresh funding BioPharma Dive

A Jim Wilson start-up will conduct the first FDA-approved tests of a form of gene editing in infants - Inquirer.com

A Jim Wilson start-up will conduct the first FDA-approved tests of a form of gene editing in infants Inquirer.com

iECURE to Present Initial OTC-HOPE Clinical Data of ECUR-506 in Ornithine Transcarbamylase Deficiency at Upcoming Medical Meetings - Business Wire

iECURE to Present Initial OTC-HOPE Clinical Data of ECUR-506 in Ornithine Transcarbamylase Deficiency at Upcoming Medical Meetings Business Wire

iECURE Appoints Brian Di Donato to Board of Directors - citybiz

iECURE Appoints Brian Di Donato to Board of Directors citybiz

About Us - FinancialContent

About Us FinancialContent

iECURE receives FDA IND clearance for OTC deficiency treatment trial - Clinical Trials Arena

iECURE receives FDA IND clearance for OTC deficiency treatment trial Clinical Trials Arena

Company: iECURE - CRISPR Medicine News

Company: iECURE CRISPR Medicine News

Precision BioSciences Announces Complete Clinical Response in First Infant Dosed by Partner iECURE in Ongoing Phase 1/2 Clinical Trial in Ornithine Transcarbamylase (OTC) Deficiency - Business Wire

Precision BioSciences Announces Complete Clinical Response in First Infant Dosed by Partner iECURE in Ongoing Phase 1/2 Clinical Trial in Ornithine Transcarbamylase (OTC) Deficiency Business Wire

iECURE Launches With $50 Million Series A Financing to Develop In Vivo Gene Insertion Approaches for Devastating Diseases - Business Wire

iECURE Launches With $50 Million Series A Financing to Develop In Vivo Gene Insertion Approaches for Devastating Diseases Business Wire

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