The Institute Of Internal Auditors (Iia) Singapore

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The Institute of Internal Auditors (IIA) Singapore is the only professional body dedicated to the advancement and development of the internal audit profession in Singapore. For more than 40 years, we have been advocating the interests of the profession and remain committed to raising the profile and standing of the internal audit profession and developing the knowledge, skills and expertise of internal auditors. Representing about 2,500 members, we enhance technical excellence through The IIA’s International Standards for the Professional Practice of Internal Auditing and Code of Ethics. Our members belong to a global community of more than 235,000 professionals in nearly 200 countries and territories who share a common vision to add value in their organisations to support the achievement of strategic objectives, which they do so by growing professionally in internal audit competence.
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Procollagen IIA mediates positive feedback control of the mouse cardiogenic transcriptional network - PNAS

Procollagen IIA mediates positive feedback control of the mouse cardiogenic transcriptional network PNAS

Tanshinone IIA Loaded Inhaled Polymer Nanoparticles Alleviate Established Pulmonary Fibrosis - ACS Publications

Tanshinone IIA Loaded Inhaled Polymer Nanoparticles Alleviate Established Pulmonary Fibrosis ACS Publications

Multimodal regulation of the osteoclastogenesis process by secreted group IIA phospholipase A2 - Frontiers

Multimodal regulation of the osteoclastogenesis process by secreted group IIA phospholipase A2 Frontiers

The Continuing Story of Class IIa Bacteriocins | Microbiology and Molecular Biology Reviews - ASM Journals

The Continuing Story of Class IIa Bacteriocins | Microbiology and Molecular Biology Reviews ASM Journals

Endothelial Conditional Knockdown of NMMHC IIA (Nonmuscle Myosin Heavy Chain IIA) Attenuates Blood-Brain Barrier Damage During Ischemia-Reperfusion Injury - American Heart Association Journals

Endothelial Conditional Knockdown of NMMHC IIA (Nonmuscle Myosin Heavy Chain IIA) Attenuates Blood-Brain Barrier Damage During Ischemia-Reperfusion Injury American Heart Association Journals

A phase I/IIa safety and efficacy trial of intratympanic gamma-secretase inhibitor as a regenerative drug treatment for sensorineural hearing loss - Nature

A phase I/IIa safety and efficacy trial of intratympanic gamma-secretase inhibitor as a regenerative drug treatment for sensorineural hearing loss Nature

Phase IIa clinical trial of complement C3 inhibitor AMY-101 in adults with periodontal inflammation - JCI.org

Phase IIa clinical trial of complement C3 inhibitor AMY-101 in adults with periodontal inflammation JCI.org

FADDDED filaments coordinate complex IIa assembly during TNF-induced apoptosis - PNAS

FADDDED filaments coordinate complex IIa assembly during TNF-induced apoptosis PNAS

Myosin IIA-related Actomyosin Contractility Mediates Oxidative Stress-induced Neuronal Apoptosis - Frontiers

Myosin IIA-related Actomyosin Contractility Mediates Oxidative Stress-induced Neuronal Apoptosis Frontiers

Results of International, Double-Blind, Randomized, Placebo-Controlled, Phase IIa Study of Interleukin-1 Blockade With RPH-104 (Goflikicept) in Patients With ST-Segment–Elevation Myocardial Infarction (STEMI) - American Heart Association Journals

Results of International, Double-Blind, Randomized, Placebo-Controlled, Phase IIa Study of Interleukin-1 Blockade With RPH-104 (Goflikicept) in Patients With ST-Segment–Elevation Myocardial Infarction (STEMI) American Heart Association Journals

PDZ-domain interactions and apical expression of type IIa Na/Pi cotransporters - PNAS

PDZ-domain interactions and apical expression of type IIa Na/Pi cotransporters PNAS

Tanshinone IIA: A Review of its Anticancer Effects - Frontiers

Tanshinone IIA: A Review of its Anticancer Effects Frontiers

Results of International, Double-Blind, Randomized, Placebo-Controlled, Phase IIa Study of Interleukin-1 Blockade With RPH-104 (Goflikicept) in Patients With ST-Segment–Elevation Myocardial Infarction (STEMI) - American Heart Association Journals

Results of International, Double-Blind, Randomized, Placebo-Controlled, Phase IIa Study of Interleukin-1 Blockade With RPH-104 (Goflikicept) in Patients With ST-Segment–Elevation Myocardial Infarction (STEMI) American Heart Association Journals

TMP269, a small molecule inhibitor of class IIa HDAC, suppresses RABV replication in vitro - Frontiers

TMP269, a small molecule inhibitor of class IIa HDAC, suppresses RABV replication in vitro Frontiers

Class IIa HDAC4 and HDAC7 cooperatively regulate gene transcription in Th17 cell differentiation - PNAS

Class IIa HDAC4 and HDAC7 cooperatively regulate gene transcription in Th17 cell differentiation PNAS

Tanshinone IIA delays liver aging by modulating oxidative stress - Frontiers

Tanshinone IIA delays liver aging by modulating oxidative stress Frontiers

Tanshinone IIA inhibits cardiomyocyte pyroptosis through TLR4/NF-κB p65 pathway after acute myocardial infarction - Frontiers

Tanshinone IIA inhibits cardiomyocyte pyroptosis through TLR4/NF-κB p65 pathway after acute myocardial infarction Frontiers

Randomized controlled phase IIa clinical trial of safety, pharmacokinetics and pharmacodynamics of tenofovir and tenofovir plus levonorgestrel releasing intravaginal rings used by women in Kenya - Frontiers

Randomized controlled phase IIa clinical trial of safety, pharmacokinetics and pharmacodynamics of tenofovir and tenofovir plus levonorgestrel releasing intravaginal rings used by women in Kenya Frontiers

Tanshinone IIA alleviates atherosclerosis in LDLR−/− mice by regulating efferocytosis of macrophages - Frontiers

Tanshinone IIA alleviates atherosclerosis in LDLR−/− mice by regulating efferocytosis of macrophages Frontiers

Tanshinone IIA promotes vascular normalization and boosts Sorafenib’s anti-hepatoma activity via modulating the PI3K-AKT pathway - Frontiers

Tanshinone IIA promotes vascular normalization and boosts Sorafenib’s anti-hepatoma activity via modulating the PI3K-AKT pathway Frontiers

Effect of tanshinone IIA for myocardial ischemia/reperfusion injury in animal model: preclinical evidence and possible mechanisms - Frontiers

Effect of tanshinone IIA for myocardial ischemia/reperfusion injury in animal model: preclinical evidence and possible mechanisms Frontiers

Combining a Universal Telomerase Based Cancer Vaccine With Ipilimumab in Patients With Metastatic Melanoma - Five-Year Follow Up of a Phase I/IIa Trial - Frontiers

Combining a Universal Telomerase Based Cancer Vaccine With Ipilimumab in Patients With Metastatic Melanoma - Five-Year Follow Up of a Phase I/IIa Trial Frontiers

Synthesis of Tanshinone IIA and Related Terpenes via a C–H Functionalization Strategy - ACS Publications

Synthesis of Tanshinone IIA and Related Terpenes via a C–H Functionalization Strategy ACS Publications

Ancient duplication, coevolution, and selection at the MHC class IIA and IIB genes of birds - Frontiers

Ancient duplication, coevolution, and selection at the MHC class IIA and IIB genes of birds Frontiers

Platelet microparticles are internalized in neutrophils via the concerted activity of 12-lipoxygenase and secreted phospholipase A2-IIA - PNAS

Platelet microparticles are internalized in neutrophils via the concerted activity of 12-lipoxygenase and secreted phospholipase A2-IIA PNAS

Design and radiosynthesis of class-IIa HDAC inhibitor with high molar activity via repositioning the - Nature

Design and radiosynthesis of class-IIa HDAC inhibitor with high molar activity via repositioning the Nature

Results of the phase IIa RADICAL trial of the FGFR inhibitor AZD4547 in endocrine resistant breast cancer - Nature

Results of the phase IIa RADICAL trial of the FGFR inhibitor AZD4547 in endocrine resistant breast cancer Nature

Class IIa HDACs inhibit cell death pathways and protect muscle integrity in response to lipotoxicity - Nature

Class IIa HDACs inhibit cell death pathways and protect muscle integrity in response to lipotoxicity Nature

Selective Inhibition of Histone Deacetylase Class IIa With MC1568 Ameliorates Podocyte Injury - Frontiers

Selective Inhibition of Histone Deacetylase Class IIa With MC1568 Ameliorates Podocyte Injury Frontiers

Standard Missile-3 (SM-3) - Missile Threat

Standard Missile-3 (SM-3) Missile Threat

Tanshinone IIA Combined With Cyclosporine A Alleviates Lung Apoptosis Induced by Renal Ischemia-Reperfusion in Obese Rats - Frontiers

Tanshinone IIA Combined With Cyclosporine A Alleviates Lung Apoptosis Induced by Renal Ischemia-Reperfusion in Obese Rats Frontiers

Cortical Organoid-on-a-Chip with Physiological Hypoxia for Investigating Tanshinone IIA-Induced Neural Differentiation - Science Partner Journals

Cortical Organoid-on-a-Chip with Physiological Hypoxia for Investigating Tanshinone IIA-Induced Neural Differentiation Science Partner Journals

Structural insights into selective interaction between type IIa receptor protein tyrosine phosphatases and Liprin-α - Nature

Structural insights into selective interaction between type IIa receptor protein tyrosine phosphatases and Liprin-α Nature

Parenteral administration of factor Xa/IIa inhibitors limits experimental aortic aneurysm and atherosclerosis - Nature

Parenteral administration of factor Xa/IIa inhibitors limits experimental aortic aneurysm and atherosclerosis Nature

Taking Stock of IIA Reform: Recent developments – Investment Treaty News - International Institute for Sustainable Development

Taking Stock of IIA Reform: Recent developments – Investment Treaty News International Institute for Sustainable Development

Tanshinone IIA Protects Against Cerebral Ischemia Reperfusion Injury by Regulating Microglial Activation and Polarization via NF-κB Pathway - Frontiers

Tanshinone IIA Protects Against Cerebral Ischemia Reperfusion Injury by Regulating Microglial Activation and Polarization via NF-κB Pathway Frontiers

The role of class IIa histone deacetylases in regulating endothelial function - Frontiers

The role of class IIa histone deacetylases in regulating endothelial function Frontiers

MDA Director Says SM-3 Block IIA Ready for Production, Unrelated to Japan's Decision to Back Out of Aegis Ashore - USNI News

MDA Director Says SM-3 Block IIA Ready for Production, Unrelated to Japan's Decision to Back Out of Aegis Ashore USNI News

Class II (IIa)-Selective Histone Deacetylase Inhibitors. 1. Synthesis and Biological Evaluation of Novel (Aryloxopropenyl)pyrrolyl Hydroxyamides - ACS Publications

Class II (IIa)-Selective Histone Deacetylase Inhibitors. 1. Synthesis and Biological Evaluation of Novel (Aryloxopropenyl)pyrrolyl Hydroxyamides ACS Publications

Let’s See If the SM-3 Block IIA Can Hit an ICBM - Hudson Institute

Let’s See If the SM-3 Block IIA Can Hit an ICBM Hudson Institute

Investment Negotiations at the WTO and the IIA Regime: Anticipating unintended interactions - International Institute for Sustainable Development

Investment Negotiations at the WTO and the IIA Regime: Anticipating unintended interactions International Institute for Sustainable Development

The antitumor natural product tanshinone IIA inhibits protein kinase C and acts synergistically with 17-AAG - Nature

The antitumor natural product tanshinone IIA inhibits protein kinase C and acts synergistically with 17-AAG Nature

Design, Synthesis, and Biological Evaluation of Potent and Selective Class IIa Histone Deacetylase (HDAC) Inhibitors as a Potential Therapy for Huntington’s Disease - ACS Publications

Design, Synthesis, and Biological Evaluation of Potent and Selective Class IIa Histone Deacetylase (HDAC) Inhibitors as a Potential Therapy for Huntington’s Disease ACS Publications

NEK9 regulates primary cilia formation by acting as a selective autophagy adaptor for MYH9/myosin IIA - Nature

NEK9 regulates primary cilia formation by acting as a selective autophagy adaptor for MYH9/myosin IIA Nature

Lockheed: SM-3 Block IIA Missile Shot Next Month Will Also Test New Aegis BMD Build - USNI News

Lockheed: SM-3 Block IIA Missile Shot Next Month Will Also Test New Aegis BMD Build USNI News

Resveratrol improves motor function in patients with muscular dystrophies: an open-label, single-arm, phase IIa study - Nature

Resveratrol improves motor function in patients with muscular dystrophies: an open-label, single-arm, phase IIa study Nature

Crystal structure of the S100A4–nonmuscle myosin IIA tail fragment complex reveals an asymmetric target binding mechanism - PNAS

Crystal structure of the S100A4–nonmuscle myosin IIA tail fragment complex reveals an asymmetric target binding mechanism PNAS

Pentagon Confirms SM-3 Block IIA Missile Missed its Target in Test This Week - USNI News

Pentagon Confirms SM-3 Block IIA Missile Missed its Target in Test This Week USNI News

Synapsin IIa Controls the Reserve Pool of Glutamatergic Synaptic Vesicles - Journal of Neuroscience

Synapsin IIa Controls the Reserve Pool of Glutamatergic Synaptic Vesicles Journal of Neuroscience

Exploring Hydrophobic Subdomain IIA of the Protein Bovine Serum Albumin in the Native, Intermediate, Unfolded, and Refolded States by a Small Fluorescence Molecular Reporter - ACS Publications

Exploring Hydrophobic Subdomain IIA of the Protein Bovine Serum Albumin in the Native, Intermediate, Unfolded, and Refolded States by a Small Fluorescence Molecular Reporter ACS Publications

Regulation of protrusion, adhesion dynamics, and polarity by myosins IIA and IIB in migrating cells - Rockefeller University Press

Regulation of protrusion, adhesion dynamics, and polarity by myosins IIA and IIB in migrating cells Rockefeller University Press

Development of Class IIa Bacteriocins as Therapeutic Agents - Lohans - 2012 - International Journal of Microbiology - Wiley Online Library

Development of Class IIa Bacteriocins as Therapeutic Agents - Lohans - 2012 - International Journal of Microbiology Wiley Online Library

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