Founded in 2016, Laekna is a science-driven, clinical-stage biotechnology company committed to bringing novel therapeutics to patients with metabolic diseases, cancer and liver fibrosis around the world.
As of December 31, 2024, Laekna has initiated seven clinical trials for LAE102, LAE002(afuresertib), LAE001 and LAE005 to address unmet medical needs in obesity and cancers.
LAE102 is our internally discovered antibody against ActRIIA. Blocking Activin-ActRII pathway could promote muscle regeneration and decrease fat mass, this positions LAE102 as a promising drug candidate for achieving quality weight control. We’ve obtained IND approvals from the FDA and the CDE for LAE102 in obesity indication and are advancing the Phase I clinical trial in China. In November 2024, Laekna entered into a clinical collaboration agreement with Eli Lilly and Company to support and accelerate global clinical development of LAE102.
Laekna team has accumulated tremendous experiences and deep know-how in the specific field of targeting ActRII receptors and is developing more drug candidates (LAE103 and LAE123), in addition to LAE102, to maximize the value of the target. LAE103 is an ActRIIB-selective antibody and LAE123 is a dual inhibitor against ActRIIA/IIB. Both are our internally discovered antibodies for muscle and other disease indications.
In the cancer area, Laekna has built a comprehensive portfolio of drug candidates including LAE002(afuresertib), LAE001 and other seven pre-clinical drug candidates. LAE002 (afuresertib) is one of the only two AKT inhibitors in late-stage development for breast and prostate cancer globally. Laekna has commenced the Phase III clinical trial (AFFIRM-205) for LAE002 in patients with HR+/HER2- breast cancer and the study recruitment is on track.
Laekna, Inc. (2105.HK) was listed on the Main Board of The Stock Exchange of Hong Kong Limited on June 29, 2023.
For more information, please visit: https://www.laekna.com/
Company Details
- Employees
- 30
- Founded
- -
- Address
- 浦东新区张江, 蔡伦路987号5楼,china
- Industry
- Pharmaceutical Manufacturing
- NAICS
-
Pharmaceutical and Medicine ManufacturingMedicinal and Botanical ManufacturingPharmaceutical Preparation ManufacturingIn-Vitro Diagnostic Substance ManufacturingBiological Product (except Diagnostic) Manufacturing
- Website
- http://www.laekna.com/
- HQ
- 上海, 上海
Laekna Questions
Laekna's website is http://www.laekna.com/
Laekna's LinkedIn profile is https://cn.linkedin.com/company/laekna
Laekna has
30 employees.
View email and phone details for 30
employees at Laekna.
Laekna's industry is
Pharmaceutical Manufacturing
Laekna's top competitors are
Harbour Biomed,
Abbvie,
Innovent Biologics,
Nucleate,
Insilico Medicine,
Odyssey Therapeutics,
Fusion Vc,
Hutchmed,
Henlius,
Gan & Lee Pharmaceuticals.
Laekna's categories are Pharmaceutical Manufacturing
Laekna's founding year is 2016
