MENTOR Program EU

The multi-disciplinary training network MSCA DN MENTOR focuses on the mTOR (mammalian/mechanistic Target Of Rapamycin) network, a central signaling hub that integrates, nutritional cues and controls cell growth and metabolism. Aberrant mTOR activity underlies a wide range of pathologies, including age-related diseases with high incidence such as cancer, obesity, and diabetes as well as rare genetic conditions, termed mTORopathies, characterized by tumor formation, polycystic kidneys, and brain manifestations. New mechanistic insights into mTORopathies will improve treatment for people living with rare conditions through strategies of personalized medicine and will open new therapeutic avenues for severe age-related pathologies. MSCA DN MENTOR program will involve 18 doctoral candidates with the overall goal of understanding and treating mTORopathies while maximizing the impact towards research and training for cancer, metabolic syndromes, and age-related disorders.