Prisma

The Digital Proteome: Unveiling the Final Frontier of Biology Prisma is advancing breakthrough protein sequencing technologies to unveil the true functional drivers of biology and transform human health. Imagine a world where we can resolve every protein within a sample, revealing its identity and quantity with stunning resolution. This is the future Prisma is building with unbiased, single-molecule protein sequencing, a revolutionary approach that analyzes proteins for hypothesis free discovery. Th BioRxiv article in our featured post dives into the core of Prisma's elegant protein sequencing technology. Our Universal Recognizer is a single, small molecule dye that binds directly to the N-terminus of proteins and produces a distinct optical fingerprint for each amino acid and post-translational modification. Combined with our cutting-edge, light-based sequencing approach, Prisma generates accurate amino acid sequences to enable unbiased, proteome-scale identification and quantification of proteins at the single-molecule level.