The Structural Genomics Consortium (Sgc)

The Structural Genomics Consortium (Sgc) company information, Employees & Contact Information

The Structural Genomics Consortium (SGC) is a global public-private partnership dedicated to accelerating drug discovery by elucidating the functions of all human proteins. Established in 2003 as a UK-registered charity with headquarters in Toronto, Canada, SGC’s pioneering open science model for protein science, chemical biology and drug discovery adheres to the principles that all data, reagents and tools generated by SGC scientists must be made publicly available. SGC is currently one of the largest and longest-running biomedical research consortia in the world with current contributions from nine Pharma industry members. Operating from leading academic institutions worldwide—including Goethe University Frankfurt, Karolinska Institutet, McGill University, University College London, the University of North Carolina at Chapel Hill, the University of Toronto, and the University of Campinas (UNICAMP)—SGC's network comprises approximately 250 scientists. This collaborative framework bridges academia and industry, uniting experts to advance our understanding of human biology and expedite the development of new therapeutics. Over the past two decades, SGC has made significant contributions to the scientific community, including the determination of thousands of protein structures and the development of numerous chemical probes. By focusing on understudied areas of the human genome, SGC provides essential tools and data that empower researchers worldwide to explore novel biological pathways and potential drug targets. Looking ahead to 2025 and beyond, SGC is committed to leveraging advancements in machine learning and computational biology to transform early drug discovery. By scaling up efforts in collaboration with the computational community, SGC aims to generate, format, and disseminate high-quality data that will democratize drug discovery.

Company Details

Employees
75
Founded
-
Address
101 College Street- Mars, South Tower,suite 700,canada
Phone
(416) 854-2745
Industry
Research Services
NAICS
Scientific Research and Development Services
Research and Development in the Physical, Engineering, and Life Sciences
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)
Website
thesgc.org
HQ
Toronto, Ontario
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The Structural Genomics Consortium (Sgc) Questions

News

The Future Impact of Machine Learning on Drug Discovery - University College London

The Future Impact of Machine Learning on Drug Discovery University College London

Therapeutic Targeting of RNA Splicing Catalysis through Inhibition of Protein Arginine Methylation - ScienceDirect.com

Therapeutic Targeting of RNA Splicing Catalysis through Inhibition of Protein Arginine Methylation ScienceDirect.com

Anti-Inflammatory Properties of Chemical Probes in Human Whole Blood: Focus on Prostaglandin E2 Production - Frontiers

Anti-Inflammatory Properties of Chemical Probes in Human Whole Blood: Focus on Prostaglandin E2 Production Frontiers

Exciting Experiments in "Open Science" by Huntington's Researchers - HDBuzz

Exciting Experiments in "Open Science" by Huntington's Researchers HDBuzz

The OICR and SGC develop and give away new drug-like molecule to help crowd-source cancer research - EurekAlert!

The OICR and SGC develop and give away new drug-like molecule to help crowd-source cancer research EurekAlert!

SGC and HitGen Announce Research Collaboration Focused on DNA-Encoded Library Based Drug Discovery - PR Newswire

SGC and HitGen Announce Research Collaboration Focused on DNA-Encoded Library Based Drug Discovery PR Newswire

The Pan-Canadian Chemical Library: A Mechanism to Open Academic Chemistry to High-Throughput Virtual Screening - Nature

The Pan-Canadian Chemical Library: A Mechanism to Open Academic Chemistry to High-Throughput Virtual Screening Nature

Chemical probe can help regulate an essential signaling pathway in cells - Agência FAPESP

Chemical probe can help regulate an essential signaling pathway in cells Agência FAPESP

Discovery of I-BRD9, a Selective Cell Active Chemical Probe for Bromodomain Containing Protein 9 Inhibition - ACS Publications

Discovery of I-BRD9, a Selective Cell Active Chemical Probe for Bromodomain Containing Protein 9 Inhibition ACS Publications

Conformational plasticity of glycogenin and its maltosaccharide substrate during glycogen biogenesis - PNAS

Conformational plasticity of glycogenin and its maltosaccharide substrate during glycogen biogenesis PNAS

Mapping of the sGC Stimulator BAY 41-2272 Binding Site on H-NOX Domain and Its Regulation by the Redox State of the Heme - Frontiers

Mapping of the sGC Stimulator BAY 41-2272 Binding Site on H-NOX Domain and Its Regulation by the Redox State of the Heme Frontiers

Southern Gas Corridor Raises Significant Financing, but Still Faces Provocations - The Jamestown Foundation

Southern Gas Corridor Raises Significant Financing, but Still Faces Provocations The Jamestown Foundation

How to Create Productive Partnerships With Universities - MIT Sloan Management Review

How to Create Productive Partnerships With Universities MIT Sloan Management Review

Identification of a Chemical Probe for Bromo and Extra C-Terminal Bromodomain Inhibition through Optimization of a Fragment-Derived Hit | Journal of Medicinal Chemistry - ACS Publications

Identification of a Chemical Probe for Bromo and Extra C-Terminal Bromodomain Inhibition through Optimization of a Fragment-Derived Hit | Journal of Medicinal Chemistry ACS Publications

A host defense peptide mimetic, brilacidin, potentiates caspofungin antifungal activity against human pathogenic fungi - Nature

A host defense peptide mimetic, brilacidin, potentiates caspofungin antifungal activity against human pathogenic fungi Nature

Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism - PNAS

Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism PNAS

The sGC stimulator BAY-747 and activator runcaciguat can enhance memory in vivo via differential hippocampal plasticity mechanisms - Nature

The sGC stimulator BAY-747 and activator runcaciguat can enhance memory in vivo via differential hippocampal plasticity mechanisms Nature

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