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What are the constituents of the solution-mixture in e-cigarette cartridges? Is the solution safe? The E-cartridge is mainly composed of propylene glycol, and a very small amount of nicotine. Propylene Glycol is a food additive found in many foods we eat today, such as food coloring, flavoring and also used to keep food, medicines and cosmetics moist. It is considered generally safe and it is the element that helps to create the vapor that simulates smoke. Nicotine is an alkaloid that is naturally present in certain plants. A high presence is found in tobacco and a low presence is found in common vegetables such as potatoes, tomatoes and green peppers. Nicotine, when delivered in small dosages such can deliver a feeling of calmness or relaxation. Current available information states that nicotine in and of it self has not been shown to promote the development of cancer in healthy tissue. Additionally, it has not been shown to have any mutagenic properties. This being said, it should also be noted that the International Agency for Research on Cancer has not evaluated nicotine as of this time. Could the e-cigarette really be substituted for an ordinary cigarette and does it really deliver the same flavor as ordinary cigarettes? The e-cigarette simulates traditional smoking, by meeting smokers physiological, psychological and behavioral needs. It offers a variety of flavors to satisfy smokers unique taste requirements and cultural backgrounds. What’s the main difference between the e-cigarette and ordinary cigarettes? The e-cigarette does not use combustion and produces no smoke; It does not produce any new substances in the process of vaporization. Furthermore, the e-cigarette, does not produce any dangerous substances such as tar carbon monoxide that are produced during ordinary smoking. It does not produce second-hand smoke that would harm family members and pollute the environment.