Akshay Neeli Email & Phone Number

Somerville, Massachusetts, US

- Implement and validate cGMP test methods involved in the manufacturing of bluebird bio drugs.- Scientific methods include flow cytometry, gene/protein expression, cell counting, cell culture analysis, qPCR, mass spectrometry etc.- Collaborate with CxOs around the world to oversee method executions.- Author technical documents such as SOPs, validation.

Lawrence Township, NJ, US

• Solved the problem of Protein Low Molecular Weight (LMW) species formation in BMS drugs to increase purity by 90%.
• Patent filed (one of three inventors).
• Established the ability of cytochrome p-450 oxidase to inhibit thioredoxin and reduce LMW species formation.

Cambridge, Massachusetts, US

• Worked on novel technology called Acoustophoretic Bioprinting. Established 100% protein stability under strong acoustic fields through morphology and binding studies.
• Became first ever team to successfully develop monodisperse microscopic polymers encapsulated with 70% mAb concentration for applications in subcutaneous drug delivery.

Manipal, Karnataka, IN

• Proved that DNA Methylation influences Glucose Metabolism at a larger extent during disease progression.
• Proved that MDA-MB-231 breast cancer cells show a 40% increase in adaptation to glucose depletion when compared to HepG2 cells.
• Established TPI1 and PYGL gene targets for improved control of glucose metabolism under the influence of DNA methylation.
• Successfully defended thesis.

Hyderabad, Telangana, IN

- Spent the internship rotating labs and repeatedly conducting several laboratory techniques to gain high levels of proficiency. - Some of these techniques include Mammalian and Microbial Cell Culturing, Cell Line Development, Bioreactor Operation, Transfection techniques, DNA/RNA Extraction and Analysis, Gel Electrophoresis, SDS-PAGE, PCR, Western Blot.

Bangalore, Karnataka, IN

- Worked on large scale waste water treatment (Reverse Osmosis).- During the process of treatment, inactivated cell mass was being produced in large amounts.- Constant land filling of the cell mass is expensive, so my research included its re-utilization.- Developed a novel method of utilizing the cell mass in construction.- Patent expected in 2020. Used.

Master Of Science - Ms, Biotechnology

Bachelor Of Science - Bs, Biotechnology