Christopher M. Johnson Email & Phone Number

Salt Lake City, UT, US

Salt Lake City

Salt Lake City, Utah

I lead cross functional teams that research, develop and adapt cutting edge methods to manipulate biology at scale.

Salt Lake City, Utah

Worked within highly cross functional teams to develop and validate methods to manipulate biology at scale.

Salt Lake City, Utah

I studied the potential therapies developed by our transformative approach in detail, validating these discoveries using independent cell and molecular techniques.

Cambridge, MA

• Working within the scope of funded grants, I identified areas of potentially high impact research and initiated new projects in those areas. I pursued these projects as an individual, as a leader of small teams and in.
• Identified genes that affect a bacteria’s ability to acquire DNA via conjugation. To facilitate my research, I adapted Tn-seq (transposon mutagenesis coupled with high-throughput sequencing) for use in Bacillus.
• Discover and understand how ICEBs1 protects its host from a virus. ICEBs1 detects when the phage SPß enters its lytic cycle and interferes with essential host processes, preventing phage reproduction and ensuring the.
• Identified and characterized a region of ICEBs1 needed for the element to replicate in its host. Initiated the project, collaborated with and mentored a junior lab member who took primary responsibility (1 peer review.
• Characterize how ICEBs1 prevents closely related mobile elements from infecting its current host. Supervised and mentored several team members in the initiation and development of this project. Show less

Greater Minneapolis-St. Paul Area

• As part of an interdisciplinary team I studied how conjugation is regulated at the molecular level in Enterococcus faecalis, a Gram positive bacterium. Collaborating with groups from several Universities, I used.
• This work resulted in 6 peer review publications, including 2 in Proc. Natl. Acad. Sci. U.S.A.
• Communicated work at national and university-wide conferences and regular lab meetings.
• Instructed other lab members in technical processes.
• Advised and assisted rotating graduate students.
• Oversaw laboratory compliance with Federal, State and University guidelines for use and disposal of radioactive materials. Show less

Greater Minneapolis-St. Paul Area

• I used in vivo and in vitro cell biology approaches to explore the role of IL-12 and other third signal cytokines in promoting an immune response (CD8+ T-cell expansion and differentiation) against model antigens and.
• This work resulted in 2 peer review publications.
• Collaborated with other lab members on projects to fulfill funding mandates.
• Advised and assisted lab members in technical processes.
• Oversaw laboratory compliance with Federal, State and… Show more I used in vivo and in vitro cell biology approaches to explore the role of IL-12 and other third signal cytokines in promoting an immune response (CD8+.
• Oversaw laboratory compliance with Federal, State and University guidelines for use and disposal of radioactive materials. Show less

Greater Minneapolis-St. Paul Area

• I investigated the effects of humoral immunity (the complement system) on eukaryotic cell membranes and xenogenic tissues.
• Developed hemolytic assays to test effects of complement on xenogenic tissues.
• Performed ELISAs for complement components.
• Analyzed data and communicated results to primary investigator and collaborators.

Doctor Of Philosophy (Ph.D.), Microbiology (Microbiology, Immunology And Cancer Biology Program)

Thesis title: Reciprocal regulation between the prgQ and prgX operons of pCF10, a conjugative plasmid of Enterococcus faecalis. • Doctoral.

Bachelor Of Science (B.S.), Biology

Research included Identifying and studying phenotypic aberrations in Drosophila melanogaster embryos containing mutations in the tumor.