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David Vance is listed as Antibody Identification and Characterization at Wadsworth Center, a company with 202 employees, based in Albany, New York, United States. AeroLeads shows a matched LinkedIn profile for David Vance.
David Vance previously worked as Research Scientist 3 at Wadsworth Center and Research Scientist 2 at Wadsworth Center. David Vance holds Ph.D., Chemical And Biological Engineering from Rensselaer Polytechnic Institute.
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I work on identifying and characterizing human antibodies against the causative agent of Lyme disease, Borrelia burgdorferi. We study the outer surface proteins OspA, OspC, DbpA, and DbpB, and are working to construct detailed B-cell epitope maps of the same.Past work involved the important biodefense agent Ricin. In collaboration with biopharmaceutical companies and the US Army, we tested candidate vaccines in vivo, and characterized the resulting immunological response for neutralizing activity in vitro, and protection in vivo. In parallel, we also identified and characterized several monoclonal antibodies (both camelid and murine, with some then being humanized) that are capable of neutralizing ricin at low doses. Recently, I have been studying computer science, programming, databases, artificial intelligence, and data visualization in order to complement my wet lab skills. I am interested in utilizing this new knowledge to supplement my career in the field of vaccine development, antibody engineering and/or bioinformatics.
Listed skills include Vaccines, Cell Culture, Elisa, Sds Page, and 17 others.
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Albany, New York Area
We are applying the tools and techniques perfected during our studies with ricin to the study of Lyme disease antigens on the Borrelia burgdorferi spirochete. We are identifying human antibodies from Lyme disease patients, mapping their epitopes, and characterizing their ability to protect mice from spirochete challenge.
Albany, New York Area
Worked under a NIAID contract award entitled "B Cell Epitope Discovery and Mechanisms of Antibody Protection," using ricin as our model antigen.
Albany, New York
-Tested candidate ricin biodefense vaccines and new adjuvants in mouse models, and characterized the antibody response.-Designed a heterodimeric, single domain camelid antibody (VHH) that can neutralize ricin in vitro and in vivo.-Used phage display, peptide arrays, competition assays, Western Blots, mutated antigens, and crystal structures to create a.
Troy, New York
-Designed and characterized polyvalent inhibitors of anthrax toxin.-Used 2- and 3-D NMR Spectroscopy to map the binding epitope of an anthrax toxin neutralizing peptide on the anthrax receptor Capillary Morphogenesis Protein 2 (CMG2).-Used phage display to identify peptides that could bind to anthrax toxin receptors, and some disease causing proteins such.
Other employees you can reach at wadsworth.org. View company contacts for 202 employees →
Beverly Hart
Colleague at Wadsworth CenterAlbany, New York, United States, United States
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Caleb Mallery
Colleague at Wadsworth CenterAlbany, New York, United States, United States
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Sujatha Kadaba
Colleague at Wadsworth CenterAlbany, New York Metropolitan Area, United States
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Beverly Rauch
Colleague at Wadsworth CenterAlbany, New York, United States, United States
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Janice Pata
Colleague at Wadsworth CenterAlbany, New York, United States, United States
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Rong Yao
Colleague at Wadsworth CenterLatham, New York, United States, United States
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Harold Burger
Colleague at Wadsworth CenterEast Greenbush, New York, United States, United States
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Liaquat Husain
Colleague at Wadsworth CenterAlbany, New York, United States, United States
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Krithivasan Sankaranarayanan
Colleague at Wadsworth CenterAlbany, New York, United States, United States
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Mike Mcgarry(Wadsworth)
Colleague at Wadsworth CenterAlplaus, New York, United States, United States
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Thesis: Design and Characterization of Polyvalent Therapeutics
Quick answers generated from the profile data available on this page.
David Vance works for Wadsworth Center.
David Vance is listed as Antibody Identification and Characterization at Wadsworth Center.
David Vance is based in Albany, New York, United States while working with Wadsworth Center.
David Vance has worked for Wadsworth Center, University At Albany School Of Public Health, and Rensselaer Polytechnic Institute.
David Vance's colleagues at Wadsworth Center include Beverly Hart, Caleb Mallery, Sujatha Kadaba, Beverly Rauch, and Janice Pata.
You can use AeroLeads to view verified contact signals for David Vance at Wadsworth Center, including work email, phone, and LinkedIn data when available.
David Vance holds Ph.D., Chemical And Biological Engineering from Rensselaer Polytechnic Institute.
David Vance is listed with skills including Vaccines, Cell Culture, Elisa, Sds Page, Western Blotting, Monoclonal Antibodies, Antibodies, and In Vivo.
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