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David W. is listed as Principal Bioinformatics Scientist at Integrated DNA Technologies at Integrated DNA Technologies, a company with 1085 employees, based in San Mateo, California, United States. AeroLeads shows a matched LinkedIn profile for David W..
David W. previously worked as Principal Bioinformatics Scientist at Integrated Dna Technologies and Senior Staff Bioinformatics Scientist at Integrated Dna Technologies. David W. holds Master Of Science (M.S.), Computer Science from Washington University In St. Louis.
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Accomplished bioinformatics R&D scientist with over a decade of experience specializing in phase-gated genomics product development, single-cell product development, NGS data analysis, and employing deep learning in NGS panel development. Demonstrated success in driving innovation and collaborating effectively with cross-functional teams, including bench scientists, software and hardware engineers, as well as legal and marketing professionals.CORE COMPETENCIES• Extensive industry background in designing a diverse array of commercialized assays and tools for genomics research and diagnostics, encompassing NGS-based products, CRISPR Cas9 off-target prediction, qPCR-based gene expression, genotyping applications, protein detection, and single-cell analysis.• Demonstrated leadership in developing NGS data analysis frameworks, adeptly managing both local clusters and cloud computing platforms.• Proficiency in deep-learning neural networks (e.g., RNN, Transformer), machine learning techniques (e.g., SVM), data visualization, data mining, and information retrieval, highlighted through released products and publications in top-tier journals.• Comprehensive utilization of genomic public datasets, seamlessly integrating them into in-house NGS pipelines and assay design workflows. Proficient in various sequence analysis tools such as Bedtools, Samtools, Picard, BWA, GATK4, Vardict, and Freebayes, along with leveraging genomic databases like NCBI, ENSEMBL, COSMIC, and UCSC browser.• Fluent in programming languages including Python, Pytorch, R, and Jupyter Notebook (employing pandas, NumPy, and matplotlib), as well as database management systems like MySQL and MongoDB. Proficient in web development technologies such as Angular, Bootstrap, Node.JS, and HTML, with a robust command of Linux.• Substantial hands-on experience in molecular biology and microbiology, complementing computational expertise.• Skilled in effectively diagnosing and resolving application issues within specified timelines.• Notable track record of innovation and publication, boasting three patents and seventeen publications, including contributions to prestigious journals such as Science, Nature, Nature Biotechnology, and Nature Methods.
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A career timeline built from the work history available for this profile.
Pioneered the integration of advanced deep learning methods, including Transformer and pretrained genome Large Language Model (LLM), to drive innovation in NGS product development and enhance CRISPR off-target prediction capabilities.Led the bioinformatics team in developing a comprehensive cancer panel for tumor molecular profiling, facilitating the.
Redwood City
Led the bioinformatics team at the Redwood site, concentrating on NGS product development. Spearheaded the creation of groundbreaking initiatives, such as the development of the next-generation hybridization capture probe design engine, xGenV3, utilizing deep-learning neural networks. Additionally, pioneered the creation of a one-tube enrichment solution.
South San Francisco, CA
Led the bioinformatics team in the development of multiple multiplex PCR-based NGS panels, such as the CFTR panel, solid tumor hotspot panel (52 genes), and pan-cancer panel (>400 genes). Focused efforts on content selection, assay design, and comprehensive data analysis.Developed innovative single-cell applications, including RNA/protein co-detection and.
South San Francisco, CA
Designed and implemented in-house DNA-Seq analysis pipelines to support the development of a range of DNA-Seq products, including targeted re-sequencing (Access Array) and single-cell DNA-Seq products (whole genome, whole exome, and targeted re-sequencing).Designed and implemented in-house RNA-Seq analysis pipelines to facilitate the development of various.
Foster City, CA
Developed and implemented a pipeline for designing SybrGreen and TaqMan real-time PCR assays to detect genome-wide DNA Methylation.Developed a Genplex pipeline for multiplexed SNP genotyping analysis.Played a pivotal role in providing bioinformatics support for all miRNA product lines at ABI, including individual miRNA TaqMan assays and TaqMan arrays..
Austin, TX
Developed the Ambion SilencerSelect siRNA product, pioneering the creation of a support vector machines (SVM) classifier for the selection of hyper-functional siRNAs (NAR 2009).Devised and executed a computational strategy to produce functional library panels for Ambion siRNAs.Conducted data analysis of non-coding small RNA from the ABI.
St. Louis, MO
Explored the expression and regulation patterns of crystallins in mammalian lens epithelial cells.Conducted analysis of microarray data to discern the crucial factors contributing to lens cataract development.Integrated expression profiling with a computational algorithm to forecast and pinpoint co-motifs within genes.
Quebec, Canada
Investigated the penicillin resistance mechanism of Streptococcus pneumoniae.Analyzed DNA sequences and clinical data to identify biomarkers within drug-resistant genes and developed probes for use in microarrays to detect antibiotic resistance genes.
Beijing, China
Researched the adhesion gene and urease gene of Ureaplasma urealyticum.Pioneered a novel method to fabricate a genus-specific probe for Listeria species utilizing randomly amplified polymorphic DNA (RAPD).
Other employees you can reach at idtdna.com. View company contacts for 1085 employees →
Aubrey Lyon
Colleague at Integrated Dna TechnologiesCedar Rapids, Iowa, United States, United States
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Putri Nurfalah
Colleague at Integrated Dna TechnologiesSingapore, Singapore
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Matthew Brown
Colleague at Integrated Dna TechnologiesUnited States, United States
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Koen Van De Put
Colleague at Integrated Dna TechnologiesLeuven, Flemish Region, Belgium, Belgium
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Alisha Fordice
Colleague at Integrated Dna TechnologiesIowa City-Cedar Rapids Area, United States
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Sarah Thayer
Colleague at Integrated Dna TechnologiesIowa City, Iowa, United States, United States
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Austin Scott
Colleague at Integrated Dna TechnologiesIowa City, Iowa, United States, United States
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Stacy Tuegel
Colleague at Integrated Dna TechnologiesNorth Liberty, Iowa, United States, United States
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Jake Mcculley
Colleague at Integrated Dna TechnologiesIowa City-Cedar Rapids Area, United States
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Dries Ma Ja
Colleague at Integrated Dna TechnologiesBelgium, Belgium
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Quick answers generated from the profile data available on this page.
David W. works for Integrated DNA Technologies.
David W. is listed as Principal Bioinformatics Scientist at Integrated DNA Technologies at Integrated DNA Technologies.
David W. is based in San Mateo, California, United States while working with Integrated DNA Technologies.
David W. has worked for Integrated Dna Technologies, Fluidigm Corporation, Life Technologies, Ambion, and Washington University School Of Medicine.
David W.'s colleagues at Integrated DNA Technologies include Aubrey Lyon, Putri Nurfalah, Matthew Brown, Koen Van De Put, and Alisha Fordice.
You can use AeroLeads to view verified contact signals for David W. at Integrated DNA Technologies, including work email, phone, and LinkedIn data when available.
David W. holds Master Of Science (M.S.), Computer Science from Washington University In St. Louis.
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