Derek Hart work email
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Derek Hart personal email
I develop NGS analysis pipelines & scripts for the CDC to modernize their surveillance of measles and mumps. I use essential bioinformatics tools everyday: Linux CLI, Snakemake, Nextflow, Python, R, Git, etc.During my PhD, I studied the fundamental physics of DNA with molecular dynamics simulations and single-molecule FRET microscopy experiments. I have extensive wet lab experience (4+ years). My publication touched on many foundational elements of DNA biophysics: force, rates, transition state, worm-like chains, excluded-volume interactions, etc.
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Data Manager, BioinformaticianAsrt, Inc. Dec 2022 - PresentAtlanta, Georgia, United StatesWorking on-site at the CDC in the Viral Vaccine Preventable Disease Branch• Built and deployed production-level NGS data analysis workflows for nationwide surveillance of measles and mumps. Extensive use of Snakemake, Nextflow, Python, Linux, and HPC systems.• Created cloud-based ETL pipeline and SQL database with Azure and Databricks to rapidly assess proficiency of >100 molecular laboratories worldwide. Features real-time data ingestion and processing.• Developed R Shiny dashboard to aggregate and visualize a global measles sequence database. Created interactive timeline charts, geographic map plots, and phylogenetic trees using popular Javascript libraries (e.g. D3, Highcharts).• Collaborated with microbiologists to optimize tiling amplicon enrichment assay, enabling high coverage depth even for high-Ct samples in non-coding regions.• Communicated methods & results in multiple peer-reviewed publications, and at multiple global network conferences. -
Graduate Research AssistantGeorgia Institute Of Technology Aug 2016 - Nov 2022Greater Atlanta Area• Designed and implemented single-molecule FRET microscopy assay to observe kinetics of short DNA duplexes subject to weak tensile force. Highly experienced with image and signal processing methods.• Performed molecular dynamics simulations on high-performance cluster (HPC). Used advanced statistical sampling methods to observe energy landscape of rare transition states. Extensive use of Python data science libraries.• 5 years of wet lab experience performing DNA/RNA-based protocols. -
Graduate Teaching AssistantGeorgia Institute Of Technology Aug 2016 - Aug 2019Atlanta, Georgia, United Stateso Evaluated exams, labs, and homework with course instructors weekly to improve student outcomeso Mentored students one-on-one during laboratory sections and office hours -
Research FellowshipNational Institute Of Standards And Technology Jun 2015 - Jul 2015Gaithersburg, Mdo Calibrated advanced mass sensor instruments used in ongoing research during an 8-week summer programo Independently learned to operate and extract data from a laser Doppler vibrometer o Presented results to a scientific audience in a public talk -
Summer InternshipLos Alamos National Laboratory May 2014 - Jul 2014Los Alamos, Nmo Explored using nuclear magnetic resonance methods to measure the water content in drought-stricken aspens in a 10-week summer program.o Presented novel methods and results in both a written report and poster presentation
Derek Hart Education Details
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Single-Molecule Biophysics -
Engineering Physics
Frequently Asked Questions about Derek Hart
What company does Derek Hart work for?
Derek Hart works for Asrt, Inc.
What is Derek Hart's role at the current company?
Derek Hart's current role is Bioinformatician | Data Manager | Biophysics PhD.
What is Derek Hart's email address?
Derek Hart's email address is de****@****ech.edu
What schools did Derek Hart attend?
Derek Hart attended Georgia Institute Of Technology, Colorado School Of Mines.
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