Eloy Hernandez Email and Phone Number
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Highly skilled, results-driven Scientist with deep expertise in inflammatory and metabolic diseases, and tumor microenvironment. Proven track record in identifying novel targets and advancing compounds through early exploratory phase into clinical development. Extensive experience developing complex in vitro assays using human primary cells and with preclinical models to determine in vivo efficacy of small molecules and siRNA compounds. Strong team player and mentor with exceptional communication skills in English and Spanish.
Lifenet Health
View- Website:
- lifenethealth.org
- Employees:
- 1327
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R And D Senior Scientist Liver DiseaseLifenet HealthSan Diego, Ca, Us
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R&D Senior Scientist Liver DiseaseLifenet Health Dec 2024 - PresentSan Diego, California, United States
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Senior Research ScientistTakeda Nov 2020 - Jul 2024San Diego, CaliforniaIdentified and interrogate 2 anti-inflammatory and 16 anti-fibrotic diseases.Developed and successfully executed in vitro pharmacology assays to identify siRNA assets as candidate compounds for the previous targetsDesigned in vitro and pre-clinical studies to determine efficacy of small molecules and siRNA assets (LNP and GalNac) to progress the next clinical stage.Successfully progressed 1 anti-inflammatory and 3 anti-fibrotic targets form early discovery phase into clinical development.Acted as a cross-functional team player and leader for the progression of my projects, and actively take decisions to in-license an external company compound to go directly into Clinical Phase 2b.Managed 1 junior Scientist Assistant who was promoted due to my mentorship to Research Associate Scientist in less than a year. Mentoring junior staff in our group (from interns to Scientist II) -
Investigator IiGnf Oct 2016 - Nov 2020La Jolla, CaliforniaExpertise in fibrosis driving projects from concept to advance stagesLead the discovery of the Mechanism of Action (MoA) of the MASH FXR agonists Flagships of Novartis (Tropifexor and Nidufexor) Lead the biology and PD biomarker identification of 1 anti-fibrotic target to be ready for clinical development. Designed, optimized and executed a successful phenotypic high-throughput screen using CRISPR technology in primary liver cells to identify more than 10 genetic drivers of hepatic stellate cell activationDevelop complex in vitro assays, incorporating biophysical properties of the extracellular matrix. -
Postdoctoral AssociateSanford Burnham Prebys Oct 2012 - Oct 2016San Diego County, California, United StatesIdentified the mechanism of action of NBR1 in macrophage M1 polarization in obesity, as a target to improve insulin sensitivity in Type 2 DiabeticsIdentified the critical role of SQSTSM1 (p62) in the tumor microenvironment as target to reduce de progression to HCC and PDAC in patients. -
Postdoctoral Associate"Severo Ochoa" Molecular Biology Institute Nov 2010 - Aug 2012Madrid, Madrid, SpainExperience in inflammatory disease: Reumathoid arthritis, Celiac disease and NFkB pathway analysisDevelopment of microbiota analysis identification
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Phd Student (Biochemistry And Biomedicine)School Of Medicine, Autonoma University Of Madrid (Facultad De Medicina Uam) Mar 2004 - Sep 2010MadridCharacterization of the regulatory promoter of glycolytic enzyme phosphofructokinase isoforms C and L.
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InternshipPharmamar Jul 2003 - Dec 2003Madrid Area, SpainInternship in the Drug Discovery area of PharmaMar pharmaceutical company. I have participated in the HTS of new drugs in the department of celular biology performing cellular assays for the discovery of HDAC inhibitors.
Eloy Hernandez Skills
Eloy Hernandez Education Details
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Biology/Biological Sciences, General -
Biology/Biological Sciences, General
Frequently Asked Questions about Eloy Hernandez
What company does Eloy Hernandez work for?
Eloy Hernandez works for Lifenet Health
What is Eloy Hernandez's role at the current company?
Eloy Hernandez's current role is R and D Senior Scientist Liver Disease.
What is Eloy Hernandez's email address?
Eloy Hernandez's email address is eh****@****gnf.org
What schools did Eloy Hernandez attend?
Eloy Hernandez attended Universidad Autónoma De Madrid, Universidad De Alcalá.
What skills is Eloy Hernandez known for?
Eloy Hernandez has skills like Molecular Biology, Biotechnology, Western Blotting, Chromatin Immunoprecipitation, Northern Blotting, Cell Culture, Co Immunnoprecipitation, Rt Pcr, Genotyping, Metagenomics, Protein Expression, Promoter Analyses.
Who are Eloy Hernandez's colleagues?
Eloy Hernandez's colleagues are Mashae Anthony, D Clary, Debbie Hutt, Jana Baadte, Matt Cooper, Yemisi Robinson, Ed Ferreol.
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