James Fransen
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James Fransen Email & Phone Number

Move Fellow at Handshake
Location: Greater Philadelphia, United States, United States 6 work roles 3 schools
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Current company
Role
Move Fellow
Location
Greater Philadelphia, United States, United States
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James Fransen is listed as Move Fellow at Handshake, a company with 583 employees, based in Greater Philadelphia, United States, United States. AeroLeads shows a matched LinkedIn profile for James Fransen.

James Fransen previously worked as Senior Research Scientist at Spark Therapeutics, Inc. and Adjunct Instructor at Ivy Tech Community College. James Fransen holds Doctor Of Philosophy (Ph.D.), Retina Physiology In The Dept Of Anatomical Sciences And Neurobiology from University Of Louisville School Of Medicine.

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Profile bio

About James Fransen

A highly skilled and team-oriented senior scientist in gene therapy with 15 years of experience in ocular research and development. Pre-clinical research includes multiple disease areas including retinitis pigmentosa, age-related macular degeneration, and glaucoma across multiple routes of administration including sub-retinal (SR), intravitreal (IVT) and suprachoroidal (SCS) delivery. Pharmaceutical industry experience includes research project management with direct CRO and contractor management with the goal of IND enabling data, development of IVT and SCS platforms, in vivo testing of viral (AAV) and non-viral (lipid and polymer-based nanoparticles) gene therapy vectors, team lead for ELN (Benchling) implementation, and internal in vivo ocular team surgical and imaging training. Species expertise includes mice, minipig and non-human primates with extensive in-life data interpretation and analysis.

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Handshake
Handshake
Move Fellow
Philadelphia, PA, US
Website
Employees
583
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6 roles

James Fransen work experience

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Senior Research Scientist

Current

Philadelphia, Pennsylvania, United States

Led a program exploring non-viral vectors for ocular gene delivery including LNP and polymer-based nanoparticles. Integral part of a team that established multiple routes of administration for viral vectors in the eye including intravitreal and suprachoroidal delivery. Led a program establishing a novel non-human primate model of wet age-related macular.

Nov 2020 - Present

Adjunct Instructor

Sellersburg

Instructor for 14 sections of Anatomy and Physiology I/II and 1 section of Biology 101 with consistently excellent anonymous student reviews each semester (4.8+ on a 5 point scale for nearly every measure).

Aug 2016 - Dec 2020

Senior Research Associate

Louisville, Kentucky Area

Led a program exploring genetic (AAV delivered endonuclease) or molecular treatments (anti-sense oligonucleotides, small molecules) for blinding eye disease in a large animal model of autosomal dominant retinitis pigmentosa (Tg-P23H miniswine).

Jun 2019 - Sep 2020

Postdoctoral Researcher

Louisville, KY

Led a project exploring the mechanisms of direction selectivity in mouse starburst amacrine cells through patch-clamp and two-photon calcium imaging. This work was the first direct evidence of bipolar cell excitatory input driving direction selectivity without requiring inhibitory input to starburst amacrine cells.

Jul 2014 - Jun 2019

Postdoctoral Fellow

Louisville, KY

I received a T32 grant through the Institute for Cellular Therapeutics (ICT) under the NIH Ruth Kirchensteiner program to lead a project exploring photoreceptor precursor cell transplantation in the P23H-Rho mini-swine model.

Jul 2013 - Jun 2014
Team & coworkers

Colleagues at Handshake

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3 education records

James Fransen education

FAQ

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What company does James Fransen work for?

James Fransen works for Handshake.

What is James Fransen's role at Handshake?

James Fransen is listed as Move Fellow at Handshake.

Where is James Fransen based?

James Fransen is based in Greater Philadelphia, United States, United States while working with Handshake.

What companies has James Fransen worked for?

James Fransen has worked for Handshake, Spark Therapeutics, Inc., Ivy Tech Community College, and University Of Louisville School Of Medicine.

Who are James Fransen's colleagues at Handshake?

James Fransen's colleagues at Handshake include Bryan Rivers, James March, Kevin Ausman, Paul Mcfadden, and Scott Hocking.

How can I contact James Fransen?

You can use AeroLeads to view verified contact signals for James Fransen at Handshake, including work email, phone, and LinkedIn data when available.

What schools did James Fransen attend?

James Fransen holds Doctor Of Philosophy (Ph.D.), Retina Physiology In The Dept Of Anatomical Sciences And Neurobiology from University Of Louisville School Of Medicine.

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