Jan Engelmann Email & Phone Number

Munich, Bavaria, Germany

Method development for genetic analyses on single-cell data. Working with Fabian Theis, Paolo Casale, and Jakub Tomczak.

Munich, Bavaria, Germany

Title: Uncertainty Quantification for Atlas-Level Cell Type TransferAbstract ⬇️Single-cell reference atlases are large-scale, celllevel maps that capture cellular heterogeneity within an organ using single cell genomics. Given their size and cellular diversity, these atlases serve as high-quality training data for the transfer of cell type labels to new datasets. Such label transfer, however, must be robust to domain shifts in gene expression due to measurement technique, lab specifics and more general batch effects. This requires methods that provide uncertainty estimates on the cell type predictions to ensure correct interpretation. Here, for the first time, we introduce uncertainty quantification methods for cell type classification on single-cell reference atlases. We benchmark four model classes and show that currently used models lack calibration, robustness, and actionable uncertainty scores. Furthermore, we demonstrate how models that quantify uncertainty are better suited to detect unseen cell types in the setting of atlas-level cell type transfer.

Berlin, Germany

Zurich, Switzerland

- developed real time forecasting infrastructure- infrastructure for real time news article popularity forecasting using Twitter streaming data

- 4 teaching positions for elementary Physics at different levels of complexity and the philosophical aspects of these theories- Took part in course on teaching methods offered by ETHTasks:- Leading an exercise class with 20 students- Bridging the gap between theory and application of physical knowledge- Discovering the challenges and opportunities presented by E-Learning thanks to the Lockdown- Correcting student assignments- Leading group discussions- Grading student semester papersPositions:- Physics 1 for Environmental Scientists (2020)- Physics 2 for Environmental Scientists (2019)- Philosophy of Physics (2018)- Physics 2 for Physics and Mathematics Students (2017)

- Innovation project within the Digital Shapers competition initiated by McKinsey & Company - Solving a real innovation challenge for CTS Eventim focused on sustainability and festivals- Working in an interdisciplinary team on a fascinating and incredibly open challenge using the Design Thinking methodology- Bringing the result of the extensive market research to life in a Web-Application

Munich Area, Germany

- Working in an agile engineering team- Developing a SaaS solution streamlining the construction industry- Working with a Django (Python), Bootstrap (CSS), React (Javascript) tech-stack in a continuous integration environment

Erlangen Und Umgebung, Deutschland

- Developing an Edge IoT solution- Using Docker Compose to build a deployable Face recognition application storing data in the Siemens Mindsphere- Building a web interface for labelling detected faces

Munich Area, Germany

- Development of an excel model to calculate earnings according to the liquidation preference for different investments- Creating slides and 1-pagers- Research activities- Assisting both managing directors

Master'S Degree, Computational Physics, Quantum Computing, Cloud Dynamics

Bachelor'S Degree, Physik