Mackenzie Harrington Email & Phone Number

Chapel Hill, NC, US

Durham, North Carolina, United States

Durham, North Carolina, United States

Raleigh-Durham, North Carolina Area

• Participated in launching of new site by validating equipment, drafting, and editing SOPs, hiring and training a new team
• Built trackers for and tracked bridging orders and special orders
• Assisted with customer complaint investigations
• Set up and maintain daily management board
• Supervises and directs staff including employee hiring, training, evaluations, and discipline.
• Aids in the creation and maintenance of the staffing schedule for the department.

Greater San Diego Area

• Train new hires in all areas of manufacturing
• Synthesizes oligos on various synthesizer platforms
• Cleaves and deprotects oligos utilizing appropriate methods
• Quantifies and samples oligos for quality control tests
• Assesses QC data accurately and makes pass/fail decisions for oligos
• Performs the purification of oligos using various techniques

Greater San Diego Area

• Synthesized polypeptides to be used as Active Pharmaceutical Ingredients (API) in clinical trials and commercial products through Fmoc and Boc synthesis
• Utilized Waters, Agilent, Varian, and Beckman HPLC platforms to perform small and large scale purifications and analysis
• Adhered to GMP and clean room standards as well as FDA regulations
• Practiced good documentation and regularly reviewed batch records for errors
• Lyophilized and weighed peptide to prepare for wet pooling, jar milling, and final packaging of finalized product
• Used the AXP Enterprise Resource Planning System to report hours and keep track of inventory

Greater San Diego Area

• Utilized various techniques to purify and process oligonucleotides. These include, but are not limited to, Ethanol Precipitation, Annealing, Cartridge Purification, Diafiltration, HPLC Purification, Pipetting, and UV.
• Analyzed final QC data of product prior to shipment to ensure product purity and identity
• Assisted with troubleshooting of problematic data
• Drafted and edited Standard Operating Procedures (SOPs)
• Assisted with training using SOPs and was a designated mentor to new members

Greater Boston Area

• Utilized Western Blots, PCR, cell culture, cloning, cell fractionation, and RNA extraction techniques on various research projects
• Worked individually on own project investigating the role of cavin-1 and caveolin-1 in breast cancer through mammalian cell culture