Mackenzie Harrington Email & Phone Number

Chapel Hill, Nc, Us

Durham, North Carolina, United States

Durham, North Carolina, United States

Raleigh-Durham, North Carolina Area

• Participated in launching of new site by validating equipment, drafting, and editing SOPs, hiring and training a new team• Built trackers for and tracked bridging orders and special orders• Assisted with customer complaint investigations• Set up and maintain daily management board• Supervises and directs staff including employee hiring, training, evaluations, and discipline.• Aids in the creation and maintenance of the staffing schedule for the department.• Assists in and reviews the development of new procedures and processes including successfully launching Large Scale Oligo Processing• Assists in the tracking of special customer orders often under timeline restrictions.• Maintains and approves timecards and PTO requests, writes, and administers performance reviews• Organizes and prioritizes workflow within the group and communicates with staff to ensure that all products are completed according to customer requirements and sent.• Communicates departmental needs to supervisor regarding quality, speed or cost potential improvements.• Collaborates with other critical operational departments or groups to ensure product completion according to customer specifications.• Interacts with all IDT personnel on issues relating to oligonucleotide manufacturing.• Documents any process deviations or non-conformances appropriately.• Troubleshoots instrument problems and submits/tracks work orders when necessary.• Keeps all work instructions and logs pertaining to processes current and initiates the creation of additional documents when necessary.• Assists in the upkeep of weekly and monthly metrics and KPIs to evaluate performance of the group.• Communicates with the department regarding production activities and management needs.• Contributes to associate engagement. Strives to improve the engagement survey results through execution of the engagement action plan.

Greater San Diego Area

• Train new hires in all areas of manufacturing• Synthesizes oligos on various synthesizer platforms• Cleaves and deprotects oligos utilizing appropriate methods• Quantifies and samples oligos for quality control tests• Assesses QC data accurately and makes pass/fail decisions for oligos• Performs the purification of oligos using various techniques• Ensures that product meets final purity guarantees through the custom purification process• Troubleshoots oligo failures and makes thoughtful sorting and purification decisions• Keeps thorough records of specialized processes in the oligo process history• Uses automated and manual lab equipment accurately; including limited maintenance, decontamination and troubleshooting activities• Utilizes computers and custom software in a Windows-based environment to complete tasks and create final product.• Adheres to safety regulations, lab SOPs, and contamination controls• Prepares, tests and monitors reagents for synthesis, purification, and quality control processes• Prioritizes incoming orders to best meet guaranteed ship deadlines• Follows documented custom instructions and aids, when applicable• Analyzes data and information for quality, consistency, and accuracy

Greater San Diego Area

• Synthesized polypeptides to be used as Active Pharmaceutical Ingredients (API) in clinical trials and commercial products through Fmoc and Boc synthesis• Utilized Waters, Agilent, Varian, and Beckman HPLC platforms to perform small and large scale purifications and analysis• Adhered to GMP and clean room standards as well as FDA regulations• Practiced good documentation and regularly reviewed batch records for errors• Lyophilized and weighed peptide to prepare for wet pooling, jar milling, and final packaging of finalized product• Used the AXP Enterprise Resource Planning System to report hours and keep track of inventory

Greater San Diego Area

• Utilized various techniques to purify and process oligonucleotides. These include, but are not limited to, Ethanol Precipitation, Annealing, Cartridge Purification, Diafiltration, HPLC Purification, Pipetting, and UV Spectroscopy for quantification• Analyzed final QC data of product prior to shipment to ensure product purity and identity• Assisted with troubleshooting of problematic data• Drafted and edited Standard Operating Procedures (SOPs)• Assisted with training using SOPs and was a designated mentor to new members

Greater Boston Area

• Utilized Western Blots, PCR, cell culture, cloning, cell fractionation, and RNA extraction techniques on various research projects• Worked individually on own project investigating the role of cavin-1 and caveolin-1 in breast cancer through mammalian cell culture