Madhavi Sivan Email & Phone Number

Fremont, California, United States

South San Francisco, California, United States

South San Francisco, California, United States

Menlo Park, California

Conduct sample analysis using various analytical techniques, including HPLC, UPLC, GC, KF, FT-IR, TLC, and LC-MS, GC-MS.Preparation of laboratory reagents and samples; operation of instruments; data analysis; preparation of analytical reports; notebook documentation.Support of various stability study protocols and execution of study tests.Contribute to the overall operations of the QC lab, including supplies inventory, lab safety, team meetings, responding to customer needs, etc.Perform LC/MS for compound characterization and identification with supervision.Maintain cGMP compliance in the laboratory.Support regulatory inspections and audits.

-Investigation of the mechanical forces responsible for stem cell death during syringe injection-Highly proficient in working with cell culture of mammalian cells and biological tests (LDH and live/dead staining) for cell viability- Modelling of shear stress on stem cells during different injection parameters using COMSOL- Development of protocols for viability tests for different cell culture types- Assisting PhD students with flow cytometry studies to optimize in vitro cell culture processes- Experienced in studying cell viability of cell cultures using confocal microscopy-Design experiments to answer fundamental questions in regenerative medicine-Interpretation of a large amount of experimental data to identify factors affecting stem cell death using Python- Study of rat movement with spinal cord injuries after hydrogel stem cell system delivery

Stanford, California

MATSCI 160: Nanomaterials LaboratoryMATSCI 250: Introduction to Materials Science, Biomaterials EmphasisMATSCI 156: Solar Cells, Fuel Cells, and Batteries: Materials for the Energy Solution

United States

Biodesign for Pediatric Virtual Healthcare: Pacify Mobile App- Worked in a team of 3 to develop an innovative mobile health platform to augment care for patients and providers- Interviewed various stakeholders to come up with the must have and nice to have criteria for mobile health app- Developed a machine learning model for the app to accurately provide a triage assessment based on symptoms experienced- Designed UI for Pacify app and won the award for best UI design

Development of a novel prototype for a ZnO-Based Piezoelectric Nanogenerator for Touchscreen Devices

Waterloo, Ontario

Project Title: Design, Fabrication, and Characterization of Multi-Segmented Metal Nanowires (MSNWs)- Development of a procedure for the fabrication of MSNWs via a hard-template electroplating technique using specific marketing/specification requirements: 1) Synthesize a milligram quantity of MSNWs in less than a few hours 2) Predict the conditions to produce MSNWs of a desired design as accurately as possible 3) Have the following specifications - 200nm in diameter, limited to segments made of palladium, platinum, silver, copper or nickel, composed of all combinations of interfaces with the five metals. 4) Able to remain intact after the isolation procedures and can handle normal mechanical stress from standard handling and SEM preparation practices- Analyze the membrane to determine the structural information such as porosity using SEM imaging and analyzed using ImageJ- Analyze and characterize the fabricated MSNWs using SEM and XRD

Waterloo, Ontario

Exploring Various Projects in Nanobiotechnology:The Polymerase Chain Reaction and Analysis Through Gel Electrophoresis - Hands on Experience with making agarose solution, preparing samples for gel loading, transferring gel, loading and running the gel, staining the gel, viewing the gel using UV imager tray- Use Bio-Rad to analyze gel electrophoresis data- Set up a PCR mix and perform amplification in thermocylcer of the beta 2 microglobulin gene. This gene is a tumour marker for some blood cell cancers and for detecting kidney damage.Synthesis and Purification of the Green Fluorescent Protein- Culturing cells of E-coli which have been transfected by a plasmid containing EGFP His-Tag- Chemically induce and lyse cells enzymatically after a certain concentration is reached- Released protein from are purified using IMAC and subsequently characterized using SDS-pageFunctional Nano-Gold Protein Assembly and Characterization- Development of a biosensor that can be used as a 'chemical nose' or drug delivery system with a little modification- Sensor is designed to interact and bind to negatively charged biomolecules such as DNA, RNA, or negatively charged peptides- Design and develop procedure to fabricate AuNPs with the appropriate ligands to bind such biomolecules

Waterloo, Ontario

- Worked on creating unique biomimetic patterned hydrophobic and hydrophilic surfaces inspired by the Namib Desert Beetle for water collection- Development of appropriate characterization techniques to mimic the desert conditions in Lab - fog, heat etc- Continuous collection of data and modification of fabrication parameters to optimize the volume of water collected- Data analysis to find relationships between patterns/areas of hydrophobic/hydrophilic surfaces, environmental conditions and volume of water droplet collected- Accomplished a first working prototype of micropatterned surface for water collection- Worked with group members for feedback and suggestions to improve water collection outputInstruments/Techniques: White Light Interferometer, Au gold sputtering, SEM, water contact angle measurements, microcontact printing, lithography, PDMS patterning, MATLAB

-Carrying out quantitative experiments on the optimization of copper extraction via segregation-Quantitative experimentation on slag penetration on coated graphite surface-Experience in operating furnaces, glove boxes, scrubber, and carrying out glass blowing

Ottawa, Canada Area

- Characterization of AlGaAs semiconductor integrated waveguides via simulations- Optimizing and designing the model of GaAs waveguide to be used in the field of optical communications via data analysis- Dispersion simulations for AlGaAs waveguide and GaAs waveguide in Lumerical Mode Solutions.- Creating promotional materials for the research team- Second price for Research Poster

- Providing assistance through emails to an online class of 745 students. - Marking weekly assignments with a one week turnaround.- Supervising the course and ensuring no technical difficulties were faced by students. - Developing the course using the feedback received from the previous terms students. - Improved user interface by developing the word count limit widget.

Master'S Degree, Materials Science

Activities and Societies: Materials Research Society Women in Engineering Science Penpals

Bachelor’S Degree, Nanotechnology Engineering