• Conduct daily system suitability check on Analytical LC/MS and Tecan Liquid Handler. Maintain instrument in good working condition. Contact a service engineer as needed. • Assist in running the preliminary screening experiments prior to sample purification and post purification sample downstream handling.•Perform and execute challenging purification separations. • Conduct large scale (grams) and micro scale (sub-mg) purification work for small molecules and peptides. • Responsible for purifying over 3000 small molecules a year. Both library and singletons. • Support lab operation. To include, but not limited to prepare reference standard, refill media/buffers for laboratory experiments when it’s needed and switch waste bin/waste solvent bottles when full.• Support all shipping and receiving samples.• Maintain general lab orderliness. Regular equipment maintenance, water bath and equipment/work space cleaning.• Assist in the maintenance of a safe working environment and operate in a safe manner.• Trains new members and writes SOPs to improve training.

- Performs wet chemistry reactions, primarily phosphorylation chemistry.- Prepares for production by reviewing production schedule; studying and clarifying specifications; calculating requirements; assembling materials and supplies.- Maintains safe and clean work environment by following standard operating procedures.- Keeps equipment operating by following operating instructions; troubleshooting breakdowns; calling for repairs. - Performs characterization assays centered around developmental improvements. - Transfers developmental improvements to manufacturing team through training/technical transfer- Documents production by accurately completing forms, reports, logs, and records of equipment and batches following good documentation practices.- Trains and mentors new team members.- Onboards new equipment with minimal supervision.- Identifies key process bottlenecks and implements process improvements to minimize bottleneck.- Updates job knowledge by participating in training opportunities.

- Operate and maintain HPLC/UPLC equipment for purification and analyticalQC.- Produce and interpret UPLC chromatograms to monitor and identifycompounds.- Perform dilutions and spectrophotometric readings to concentrate compounds- Operate and maintain rotary evaporator equipment to concentrate compounds.- Document production by accurately completing forms, reports, logs andrecords of equipment and batch record following good documentationpractices.- Edit SOPs to improve laboratory processes and increase safety.- Perform projects based on project improvements and scale-up.

• Investigate the role of presynaptic GABA-B auto-inhibition in modulating dentategyrus network excitability and generation of dentate spikes• Prepared perfused rat' brain and underwent slicing with a vibratome• Performed several methods of immunohistochemistry staining, Nissl staining, etc.• Analyzed brain slices for cell counting to formulate analytical reports of thedentate gyrus