KEYSTONE ADVISORS is a consulting firm providing highly focused advisory services for early-stage medical device companies and private equity firms. Our firm has significant experience organizing companies, securing private equity investments, completing acquisitions and mergers, negotiating licensing agreements and divestitures.We assist entrepreneurs and early-stage companies by providing marketing intelligence and commercial assessments, developing and refining business plans… Show more KEYSTONE ADVISORS is a consulting firm providing highly focused advisory services for early-stage medical device companies and private equity firms. Our firm has significant experience organizing companies, securing private equity investments, completing acquisitions and mergers, negotiating licensing agreements and divestitures.We assist entrepreneurs and early-stage companies by providing marketing intelligence and commercial assessments, developing and refining business plans, managing fund-raising efforts and strategic transactions including shadow negotiations. For private equity firms, we provide interim management of portfolio companies, entrepreneur-in-residence projects, market and reimbursement assessments, due diligence and resource identification. We approach every assignment with two objectives - to obtain the maximum value for your enterprise and to complete each project as quickly and efficiently as possible. Show less

Aegea Medical is private, venture-backed company that developed a treatment for abnormal uterine bleeding (menorrhagia). Investors include Alloy Ventures, Delphi Ventures, Medtronic, Biomed Ventures and Solas Venture Capital. The company was acquired by Cooper Surgical in February 2021.

CoAlign Innovations was a private, venture-backed company that developed and marketed an expandable interbody device for spine surgery. Investors included Alloy Ventures and Medtronic. The company was sold to Stryker Corporation in March 2014 for $60 million.

Baronova is private, venture-backed company that is developing a novel, endoscopically delivered treatment for obesity. Investors include ONSET Ventures, Highland Capital Partners, Sante Ventures, Boston Scientific, Lumira Capital, Longitude Capital and Delos Capital.

Relievant Medsystems is a private, venture-backed company that is developing a minimally invasive treatment for low back pain. Investors include New Enterprise Associates, Canaan Partners, Morgenthaler Ventures, ONSET Ventures and Emergent Venture Partners.In November 2023, Relievant was acquired by Boston Scientific for $950 million.

Intuity Medical is a private, venture-backed company that is developing a novel blood glucose monitoring system. Investors include Investor Growth Capital, USVP, Accuitive Medical Ventures, Venrock Capital, Versant Ventures and Emergent Medical Partners.

Gynesonics is a private, venture-backed, women's health company that is developing a novel treatment for fibroids. Investors include Abingworth Management, Interwest Partners, HBM Partners, Endeavorvision and ATV.

Bioventrix is a private, venture-backed company that is developing a novel treatment for heart failure.

Adiana was a private company that developed a novel permanent contraceptive. Investors included Abingworth Management, Alloy Ventures, Boston Scientific Corporation, Charter Ventures, Delphi Ventures, Forward Ventures, Orbimed and Tullis-Dickerson. The company was sold to Cytyc Corporation (which was subsequently acquired by Hologic) for $217 million.

Estech was a private, venture-backed company that developed products for open heart surgery procedures. Investors included Psilos Venture Capital, Telegraph Hill Partners, Saints Capital, NBGI Ventures, Tullis Health Partners and Waveland Venture Partners. The company was sold to Atricure in December 2013 for $34 million.

General Surgical Innovations was a public company that developed and marketed products for vascular and open heart surgery. Investors included Brentwood Associates, Hancock Venture Partners, Norwest Equity Partners, Schroder Ventures, Tom Fogarty and Three Arch Partners. The company went public in 1997 and was acquired by Tyco Corporation in 2000 for $100 million.

LocalMed was a private, venture-backed company that developed drug and stent delivery systems that were used in interventional cardiology. Investors included New Enterprise Associates, Brentwood Associates, Hambrecht & Quist, Schroeder Venutures, Abbott Laboratories and Johnson & Johnson. The company's assets were acquired by Abbott Laboratories in 1998.

Therox is a private, venture-backed company that is developing a delivery system to provide super-saturated oxygenated solutions for patients with compromised cardiac function. Investors include Klein Perkins, DAG Ventures, Aperture Venture Partners, Wasatch Advisors, Integral Capital Partners and New Science Ventures..

InnerDyne was a public company that developed and marketed devices used in critical care. Investors included Burr, Egan Deleage & Company and Weiss, Peck & Greer. The company went public through a reverse merger with Cardiopulmonics in 1994 and was subsequently acquired by Tyco Corporation in 2000 for $180 million.

Pilot Cardiovascular was a private, venture-backed company that developed a steerable guidewire for use in coronary angioplasty procedures. Investors included Alta Partners and DSV Partners. The company was sold to C. R. Bard in 1993 for $37 million.

Datascope was a public company that developed critical care devices including an intra-aortic balloon pump, patient monitoring equipment, vascular closure devices and angioplasty products. Datascope was a public company and was acquired by Macquet in 2009 for $841 million.

Uros was a private, venture-backed company that developed a drug delivery system to treat bladder disorders. Investors included Weiss, Peck & Greer, Alta Partners, Spray Venture Fund and Three Arch Partners.

Camino Laboratories was a private, venture-backed company that developed and marketed a system to monitor intracranial pressures for critically ill patients. Investors included Sequoia Capital, Mayfield Ventures, Menlo Ventures, Pfizer Healthcare Ventures, Domain Associates and 3i Ventures, The company was acquired by Integra Life Sciences for $40 million.