Paul Willard Email and Phone Number
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I'm a biochemist with a broad educational background crossing microbiology, chemical engineering, pathology and immunology. I have 5 years of industry experience doing analytical and biochemical characterizations of antibody drug substance/product. My PhD research delved into the biochemistry and function of an E3 ubiquitin ligase, the Natural Killer Lytic Associated Molecule (NKLAM/RNF19B), important to immune cell function. This E3 ligase was found to have cytolytic effects, negatively regulating tumor cell proliferation and inducing apoptosis. • Confident speaker with experience talking in interdisciplinary groups• Trained as a biochemist with experience in protein purification, enzymatic assays, cell culturing and cell based assays.• Always looking to expand on my skills and broaden my expertise• Highly adaptable and quick to learn
Milliporesigma
View- Website:
- sigmaaldrich.com
- Employees:
- 4902
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Immunoassay Development ExpertMilliporesigma Sep 2024 - PresentSt Louis, Missouri, United StatesQuickly adapted to assay development for Single Molecule Counting (SMC®) Singulex® platform. Identified and initiated a plan to address issues with an analyte panel for neuro targets to re-launch an improved product. Implementing interferometry (BLITz/Octet) methods for identification of and go/no-go decision making for antibodies used in SMC platform. Additionally, testing binding kinetics before and after antibody labeling.
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Phd Candidate, Graduate Research AssistantSt. Louis University School Of Medicine Aug 2017 - Dec 2024Greater St. Louis AreaSuccessfully verified NKLAM function as an E3 ubiquitin ligase in vitro and characterized physiologic impact to cellular homeostasis. Discovered novel behavior of NKLAM independent of ligase function. Gained insight into possible contribution NKLAM has on natural killer cell immune function. Created multiple cells lines with controlled expression of NKLAM and NKLAM mutants for future work on impact to immune function. -
Research Associate IiiRegeneron Pharmaceuticals Apr 2012 - Feb 2017Tarrytown, NyData collection and analysis of antibody drug substance/product for chemical and biophysical characterization packages included in IND and BLA submissions to the FDA and other agencies. Process development, PPQ, and conformance batch testing. Ensured fast turnaround on internal and external information requests to support drug development and approval processes. Successfully developed in-house analytical ultracentrifugation methods to reduce the need for outsourcing data collection to contract research organizations. Performed independent research projects to enhance the depth of biochemical characterization data and improve quality of existing methods. Developed a method for detection of low-abundance serum proteins by asymmetric flow field-flow fractionation (AF4). -
Lab TechnicianUniversity Of Tennessee Jan 2008 - Aug 2008Purified proteins via IMAC and IEX-HPLC methods. Managed and maintained cyanobacterial cultures. Conducted routine equipment maintenance. Initiated characterization of the macromolecular phycobilisome protein complex.Awarded an NSF fellowship for graduate studies in Chemical and Biomolecular Engineering. -
Emergency Medical TechnicianRural/Metro Corporation Jun 2005 - Dec 2007A part-time position during my undergraduate studies. As a team, my partner and I were responsible for patient care and transportation. Additionally, I was expected to maintain equipment and keep accurate records of patient care.
Paul Willard Skills
Paul Willard Education Details
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Pathology/Experimental Pathology -
Bioengineering -
Chemical And Biomolecular Engineering
Frequently Asked Questions about Paul Willard
What company does Paul Willard work for?
Paul Willard works for Milliporesigma
What is Paul Willard's role at the current company?
Paul Willard's current role is PhD in Pathology (Biochemistry, Immunology, Cell Biology, Enzymology) | MS in Chemical Engineering (Protein Biochemistry) | BS in Microbiology. Versatile scientist working in biochemistry and cellular biology..
What is Paul Willard's email address?
Paul Willard's email address is pa****@****ail.com
What is Paul Willard's direct phone number?
Paul Willard's direct phone number is +191484*****
What schools did Paul Willard attend?
Paul Willard attended Saint Louis University School Of Medicine, University Of Tennessee, Knoxville, University Of Tennessee-Knoxville.
What skills is Paul Willard known for?
Paul Willard has skills like Gel Electrophoresis, Biochemistry, Sds Page, Hplc, Elisa, Protein Purification, Chromatography, Centrifugation, Spectrophotometry, Ief, Electrophoresis, Affinity Chromatography.
Who are Paul Willard's colleagues?
Paul Willard's colleagues are David Ferrazza, Roy Street, Olivia Osborne, Daniel Brooks, Michael Mitchell, Candy Gao, Brandyn Kerscher.
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