I'm an ICU specialist and clinical trialist. I'm a Professor of Critical Care Research at Monash University, Director of Research for St John of God Healthcare, and a ICU consultant at St John of God Subiaco and the Mount Hospital.I've been an investigator on trials with an accumulated sample size of more than 60,000 patients, am a named investigator on more than $175 M of competitive research funding, and have published more than 200 manuscripts including multiple manuscripts in NEJM (11) and JAMA (12).I have experience with Bayesian adaptive platform trials and other innovative designs such as cluster cross-over trials. I was one of four foundation members and the inaugural global leader of the REMAP-CAP platform trial that reported the treatment effect of 18 different interventions for patients with severe COVID-19 infection. The results from REMAP-CAP were incorporated rapidly into international guidelines and used to guide treatment for millions of patients, saving countless lives.I'm a board advisor for Reliis pharmaceuticals which is in the business of developing reformulations of existing drugs to solve new clinical problems.