• Design, development, qualification, and validation of In-Vitro functional assays and characterization assays for the evaluation of potencies for different anti-VEGF and anti-PD1 molecules.• Computational analysis of potencies for Biosimilars and their related product using 4PL curves and parallel line analysis tools.• Biosimilarity assessment of various molecules using cell-based functional assay and ELISA-based binding assays.• Preparation and reviewing of project-specific… Show more • Design, development, qualification, and validation of In-Vitro functional assays and characterization assays for the evaluation of potencies for different anti-VEGF and anti-PD1 molecules.• Computational analysis of potencies for Biosimilars and their related product using 4PL curves and parallel line analysis tools.• Biosimilarity assessment of various molecules using cell-based functional assay and ELISA-based binding assays.• Preparation and reviewing of project-specific protocols and reports (MOA, MDR, AMVR, etc.)• Maintenance of GMP lab and lab-specific instruments and preparation, reviewing of SOPs for GMP equipments and instruments through Electronic data management system (EDMS).• Department Training Coordinator (DTC)-preparation, and allocation of SOPs through Learning management system (LMS), LMS data punching, and ILT based trainings to colleagues and new joiners.• QMS-related activities CCR, planned and unplanned deviation (PD&UPD). • Appearance in internal QA, external CQA, and local FDA audit programs.• Communication and sharing of scientific talks, project updates, and project planning at departmental forums and higher management. Show less

• Functional characterization of monoclonal and bispecific antibodies by accessing the activation of different cellular markers, T cells and cell proliferation assays using Incucyte® Live-Cell Analysis Systems and Flow Cytometry.• Potency determination of different humanized antibodies using different cell-based assays such as ADCC, CDC and ADCP.• Generation of monoclonal antibodies using Hybridoma technology and Molecular cloning.• Generation of CAR-T cells and stable cell lines… Show more • Functional characterization of monoclonal and bispecific antibodies by accessing the activation of different cellular markers, T cells and cell proliferation assays using Incucyte® Live-Cell Analysis Systems and Flow Cytometry.• Potency determination of different humanized antibodies using different cell-based assays such as ADCC, CDC and ADCP.• Generation of monoclonal antibodies using Hybridoma technology and Molecular cloning.• Generation of CAR-T cells and stable cell lines expressing different cancer targets and scFv fragments using lentiviral transfection method in suspension and adherent cell lines for cell based assays.• Small scale transient transfection using ExpiCHO cell-based system• Purification of antibodies using column chromatography technique. Show less

Generation of monoclonal antibodieso From different strains of mice against different proteins, peptides and small molecules using standard immunization protocol and gene gun technology.o Against complex antigens using subtractive immunization strategies (Neonatal and adult tolerization).o From Single B cell cloning and V gene sequencing.Functional characterization of monoclonal antibodies by accessing the activation of different cellular markers, T cells and cell proliferation… Show more Generation of monoclonal antibodieso From different strains of mice against different proteins, peptides and small molecules using standard immunization protocol and gene gun technology.o Against complex antigens using subtractive immunization strategies (Neonatal and adult tolerization).o From Single B cell cloning and V gene sequencing.Functional characterization of monoclonal antibodies by accessing the activation of different cellular markers, T cells and cell proliferation assays. Show less

Project pipeline planningExecuting complex antibody generation projectsLeading a team in Polyclonal antibody division while conducting training and industrial visit sessions for college students.

Managing teams in Polyclonal antibody, Molecular Biology and Antibody Purification divisions

Generating Polyclonal Antibodies, Antibody labelling and Purification, Managing animal house operations, bioconjugation and molecular biology projects.Create client databases from different institutes as well as Bio-Pharma and Vaccine production industries to explore a huge market for our product and Formal interactions with clients